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Isobutaneboronic acid

Description Reference
Product Name
Isobutaneboronic acid
CAS No.
84110-40-7
Chemical Name
Isobutaneboronic acid
Synonyms
ISOBUTYLBORONIC ACID;(2-METHYLPROPYL)BORONIC ACID;2-Methylpropaneboronic acid;Isobutylboronic;RARECHEM AH PB 0258;FUB-144 fubamb 5fadb;isobutaneboronic acid;1-ISOBUTANEBORONIC ACID;Bortezomib Impurity N17;Isobutylboronic Acid, 95+%
CBNumber
CB9729575
Molecular Formula
C4H11BO2
Formula Weight
101.94
MOL File
84110-40-7.mol
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Isobutaneboronic acid Property

Melting point:
108-111 °C(lit.)
Boiling point:
180.0±23.0 °C(Predicted)
Density 
0.910±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Acetonitrile (Slightly), DMSO, Methanol (Slightly)
pka
10.49±0.43(Predicted)
form 
Crystalline Powder or Flakes
color 
White to cream
CAS DataBase Reference
84110-40-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
TSCA 
No
HazardClass 
IRRITANT
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
346225
Product name
(2-Methylpropyl)boronic acid
Purity
≥95.0%
Packaging
1g
Price
$21.84
Updated
2024/03/01
Sigma-Aldrich
Product number
346225
Product name
(2-Methylpropyl)boronic acid
Purity
≥95.0%
Packaging
5g
Price
$62.4
Updated
2024/03/01
TCI Chemical
Product number
I0597
Product name
Isobutylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$64
Updated
2024/03/01
TCI Chemical
Product number
I0597
Product name
Isobutylboronic Acid (contains varying amounts of Anhydride)
Packaging
25g
Price
$254
Updated
2024/03/01
Alfa Aesar
Product number
H27698
Product name
Isobutylboronic acid, 97%
Packaging
1g
Price
$25.65
Updated
2024/03/01
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Isobutaneboronic acid Chemical Properties,Usage,Production

Description

Isobutaneboronic acid is also known as isobutylboronic acid. Isobutaneboronic acid has been used to synthesize potent and selective dipeptidyl boronic acid proteasome inhibitors, which are promising therapeutics to treat cancer and inflammatory diseases.1

Reference

J. Adams, M. Behnke, S. Chen, A. A. Cruickshank, L. R. Dick, L. Grenier, J. M. Klunder, Y. Ma, L. Plamondon, R. L. Stein, Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids, Bioorganic & Medicinal Chemistry Letters, 1998, vol. 8, pp. 333-338

Chemical Properties

White to Almost white powder to crystal

Uses

suzuki reaction

Uses

2-Methylpropylboronic Acid is used in the preparation of isocoumarin analogs as inhibitors of γ-secretase cleavage. Also used in the preparation of peptide boronc acid.

Uses

(2-Methylpropyl)boronic acid can be used as:
A reactant in the preparation of 4-isobutylisoquinoline from 4-bromoisoquinoline by Suzuki-Miyaura type couple reaction.
A catalyst along with aluminum hydroxide, boric acid in the polymerization of styrene.
It can also be used as a reactant in:
Copper catalyzed cross-coupling reactions.
The synthesis of polyborylalkanes by Ir-catalyzed C-H borylation reaction.
The preparation of heterosubstituted diazaboroles and borinines.

Isobutaneboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Isobutaneboronic acid Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from Isobutaneboronic acid manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Isobutylboronic Acid 84110-40-7
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-05-14
Jinan Finer Chemical Co., Ltd
Product
Isobutylboronic Acid 84110-40-7
Price
US $11.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100mt
Release date
2023-08-29
Baoji Guokang Bio-Technology Co., Ltd.
Product
Isobutaneboronic acid 84110-40-7
Price
US $253.00/g
Min. Order
100g
Purity
98%
Supply Ability
1kg
Release date
2021-06-04

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