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Esomeprazole magnesium trihydrate

Product Name
Esomeprazole magnesium trihydrate
CAS No.
217087-09-7
Chemical Name
Esomeprazole magnesium trihydrate
Synonyms
Nexium;EsomepazoleTrihydrate;Esomeprazole Mg Trihydrate;ESOPMEPRAZOLE MG TRIHYDRATE;EsoMeprazole Meg. Trihydrate;Omeprazole 8.5%/12.5% pellels;Esomeprazole Magnesium (10 mg);Esomeprazole Magnesium (25 mg);Omeprazole Magnesium Trihydrate;EsoMeprazole Magnesiu Trihydrate
CBNumber
CB9740619
Molecular Formula
C34H38MgN6O7S2
Formula Weight
731.14
MOL File
217087-09-7.mol
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Esomeprazole magnesium trihydrate Property

Melting point:
184-189°C (dec.)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Slightly soluble in water, soluble in methanol, practically insoluble in heptane.
InChI
InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;
InChIKey
VEVZQDGATGBLIC-UHFFFAOYSA-N
SMILES
C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O
CAS DataBase Reference
217087-09-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
HS Code 
2933399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1585
Product name
Esomeprazole Magnesium
Packaging
1g
Price
$193
Updated
2024/03/01
Sigma-Aldrich
Product number
1249789
Product name
Esomeprazole magnesium
Purity
UnitedStatesPharmacopeia(USP)ReferenceStandard
Packaging
100MG
Price
$483
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001028
Product name
Esomeprazole magnesium trihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001028
Price
$154
Updated
2024/03/01
ChemScene
Product number
CS-1024
Product name
Esomeprazole magnesium trihydrate
Packaging
50mg
Price
$156
Updated
2021/12/16
ApexBio Technology
Product number
A3399
Product name
Esomeprazole magnesium trihydrate
Packaging
50mg
Price
$205
Updated
2021/12/16
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Esomeprazole magnesium trihydrate Chemical Properties,Usage,Production

Chemical Properties

Off-White Powder

Uses

S-Form of Omeprazole. Gastric proton-pump inhibitor

Uses

Esomeprazole Magnesium Trihydrate is used in preparation of esomeprazole magnesium trihydrate.

Uses

esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.

  1. Zollinger-Ellison syndrome
  2. Peptic ulcer, site unspecified
  3. Duodenal ulcer
  4. Gastric ulcer
  5. Gastro-oesophageal reflux disease
Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
  1. Gastro-Oesophageal Reflux Disease (GORD):
  2. treatment of erosive reflux oesophagitis;
  3. long-term management of patients with healed oesophagitis to prevent relapse;
  4. symptomatic treatment of gastro-oesophageal reflux disease (GORD).
In combination with appropriate antibiotics for:
  1. healing of duodenal ulcer associated with Helicobacter pylori;
  2. eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
  3. Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
  4. Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
  5. Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.

brand name

Nexium (AstraZeneca).

Biological Activity

Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent, orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release by inhibiting V-H+-ATPases.

Esomeprazole magnesium trihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Esomeprazole magnesium trihydrate manufacturers

Sinoway Industrial co., ltd.
Product
Esomeprazole Magnesium Trihydrate 217087-09-7
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
99% up, EP9.0, CEP
Supply Ability
20 tons
Release date
2022-08-12
Hebei Guanlang Biotechnology Co., Ltd.
Product
Esomeprazole magnesium trihydrate 217087-09-7
Price
US $25.00/pc
Min. Order
100G
Purity
99.5%
Supply Ability
100 mt
Release date
2021-06-15
Sigma Audley
Product
Esomeprazole magnesium trihydrate 217087-09-7
Price
US $35.00-25.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
200tons/year
Release date
2024-03-15

217087-09-7, Esomeprazole magnesium trihydrateRelated Search:

Magnesium sulfate heptahydrate Dimethyl sulfoxide Magnesium oxide Esomeprazole Magnesium sulfate Esomeprazole magnesium (Trifluoromethoxy)benzene Benzimidazole Dimethyl sulfate Dimethyl ether Anisole Dimethyl carbonate Dimethyl fumarate Dimethyl phthalate ETHANE Esomeprazole sodium Magnesium stearate p-Anisidine Esomeprazole Magnesium Trihydrate Usp Omeprazole Magnesium Trihydrate

  • ESOMEPRAZOLE MAGNESIUM TRIHYDRATE
  • bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate
  • (T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium
  • Nexium
  • ESOPMEPRAZOLE MG TRIHYDRATE
  • 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-1-ide
  • 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
  • 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
  • EsoMeprazole Meg. Trihydrate
  • Esomeprazole Magnesium (10 mg)
  • ESOMEPRAZOLE MAGNESIUM TRIHYDRATE USP
  • (S)-OMeprazole MagnesiuM trihydrate
  • MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, hydrate (1:3), (T-4)-
  • Magnesium,bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, hydrate
  • Esomeprazole magnesium trihydrate Bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzylimidazole-1-yl) magnesium trihydrate
  • Esomeprazole Magnesium (25 mg)
  • EsoMeprazole Magnesiu Trihydrate
  • Esomeprazole magnesium thihydrate
  • Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, hydrate (1:3), (T-4)-
  • Esomeprazole Magnesium Dihydrate/Trihydrate
  • Esomeprazole agnesium trihydrate
  • Omeprazole Magnesium Trihydrate
  • Esomeprazole magnesium trihydrate CRS
  • Nesomeprazole magnesium trihydrate
  • EsomepazoleTrihydrate
  • Esomeprazole Magnesium (1249789)
  • Omeprazole(Esomeprazole Magnesium) Trihydrate
  • Esomeprazole Magnesium Tri-Hydrate IP/Ph. Eur./BP
  • Omeprazole 8.5%/12.5% pellels
  • Esomeprzole magnesium Trihydrate
  • Esomperazole Magnessium Trihydrate
  • Esomeprazole Mg Trihydrate
  • 217087-09-7
  • C34H42MgN6O9S2
  • 2C17H18N3O3SMg3H2O
  • C34H36MgN6O6S23H2O
  • 71312
  • Acid pump inhibitors
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals