ChemicalBook > CAS DataBase List > 4-Amino-5-aminomethyl-2-methylpyrimidine

4-Amino-5-aminomethyl-2-methylpyrimidine

Product Name: 4-Amino-5-aminomethyl-2-methylpyrimidine
CAS No.: 95-02-3
Chemical Name: 4-Amino-5-aminomethyl-2-methylpyrimidine
Synonyms: Grewe DiaMine;4-amino-2-methylpyrimidine-5-methylamine;2-methyl-4-amino-5-aminomethylpyrimidine;Thiamine Impurity 16;Thiamine Impurity 48;Thiamine Impurity 34;Vitamin B1 Impurity 9;Diazinon Impurity 6 (Diazoxon);Thiamine /Vitamin B1 Impurity 19;2-Methyl-4-aminopyrimidine-5-methanamine
CBNumber: CB9757404
Molecular Formula: C6H10N4
Formula Weight: 138.17
MOL File: 95-02-3.mol

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4-Amino-5-aminomethyl-2-methylpyrimidine Property

Melting point:: 270-272°C
Boiling point:: 121-125 °C
Density: 1.207
vapor pressure: 0.012-0.019Pa at 20-25℃
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form: Solid
pka: 7.70±0.29(Predicted)
color: Off-White to Beige
PH: 10.65 at 20℃ and 10g/L
InChI: InChI=1S/C6H10N4/c1-4-9-3-5(2-7)6(8)10-4/h3H,2,7H2,1H3,(H2,8,9,10)
InChIKey: OZOHTVFCSKFMLL-UHFFFAOYSA-N
SMILES: C1(C)=NC=C(CN)C(N)=N1
LogP: -2.27 at 20℃ and pH7
Surface tension: 72.77mN/m at 1g/L and 20℃

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2633
Product name: 4-Amino-5-aminomethyl-2-methylpyrimidine
Packaging: 200MG
Price: $211
Updated: 2025/07/31

TRC

Product number: A581865
Product name: 4-Amino-5-aminomethyl-2-methylpyrimidine
Packaging: 1g
Price: $440
Updated: 2021/12/16

Usbiological

Product number: A1374-66
Product name: 4-Amino-5-aminomethyl-2-methylpyrimidine, Dihydrochloride
Packaging: 500mg
Price: $460
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA17606
Product name: 4-Amino-5-aminomethyl-2-methylpyrimidine
Packaging: 2g
Price: $520
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 6342
Product name: 4-Amino-5-aminomethyl-2-methylpyrimidine
Packaging: 1g
Price: $790
Updated: 2021/12/16

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4-Amino-5-aminomethyl-2-methylpyrimidine Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Substrate for TenA enzyme in the thiamin salvage pathway

Definition

ChEBI: An aminopyrimidine compound having its amino substituent at the 4-position together with methyl and aminomethyl substituents at the 2- and 5-positions respectively.

Synthesis

In an autoclave, the mixture of 4-Amino-5-aminomethyl-2-methylpyrimidine (2.0 kg, 15 mol), modified Raney nickel (wet weight 300 g), and saturated methanol solution of ammonia (20 L) was heated to 100 ℃ and stirred for 5 h at this temperature under 4 MPa hydrogen pressure. Then, the mixture was cooled to room temperature and filtered; 4-Amino-5-aminomethyl-2-methyl pyrimidine was obtained as a white solid (2.0 kg, 98%) by concentrating the filtrate[1].

References

[1] Lei Zhao, Fen-Er Chen, Xiao-Dong Ma. “Development of Two Scalable Syntheses of 4-Amino-5-aminomethyl-2-methylpyrimidine: Key Intermediate for Vitamin B1.” Organic Process Research & Development 16 1 (2011): 57–60.

4-Amino-5-aminomethyl-2-methylpyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Amino-5-aminomethyl-2-methylpyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Amino-5-aminomethyl-2-methylpyrimidine 95-02-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000KG
Release date: 2024-08-14

Dideu Industries Group Limited

Product: 4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE 95-02-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-13

95-02-3, 4-Amino-5-aminomethyl-2-methylpyrimidine Related Search:

Thiamine disulfide Thiamine chloride Cocarboxylase Nimustine Prosultiamine THIAMINE MONOPHOSPHATE CHLORIDE Amprolium Hydrochloride Thiamine nitrate 4-Amino-5-aminomethyl-2-methylpyrimidine Cocarboxylase tetrahydrate Amprolium 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium dodecyl sulfate 5-PYRIMIDINEMETHANAMINE 2-Methylpyrimidine HYDROXYETHYLTHIAMINE HYDROCHLORIDE 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE THIAMINE DISULFIDE NITRATE THIOCHROME

4-AMINO-2-METHYL-5-PYRIMIDINEMETHANAMINE, DIHYDROCHLORIDE

4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE

4-amino-2-methylpyrimidine-5-methylamine

5-Pyrimidinemethanamine, 4-amino-2-methyl- (9CI)

5-(Aminomethyl)-4-amino-2-methylpyrimidine

5-PyriMidineMethanaMine,4-aMino-2-Methyl-

4-Amino-5-aminomethyl-2-methylpyrimidine hydrochloride

2-methyl-4-amino-5-aminomethylpyrimidine 2HCl

2-methyl-4-amino-5-aminomethylpyrimidine

4-Amino-2-methyl-5-pyrimidinemethanamine,dihydrochlorine

2-Methyl-4-aminopyrimidine-5-methanamine

2-Methyl-5-(aminomethyl)-4-pyrimidinamine

5-Aminomethyl-2-methyl-4-pyrimidineamine

(4-amino-2-methyl-pyrimidin-5-yl)methylamine

Grewe DiaMine

Thiamine Impurity 16

4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE, DIHYDROCHLORIDE ISO 9001：2015 REACH

Thiamine Impurity 48

4-AMINO-5-AMINOMETHYL-2-METHYLPYRIMIDINE

Diazinon Impurity 6 (Diazoxon)

Vitamin B1 Impurity 9

Thiamine /Vitamin B1 Impurity 19

Thiamine Impurity 34

4-amino-2-methyl-5-(aminomethyl)Pyrimidine

95-02-3

C6H12Cl2N4

C6H10N42HCl

Bases & Related Reagents

Nucleotides

Amines

Aromatics

Enzyme substrates

Heterocycles

Nucleotides and Nucleosides

Heterocycle-Pyrimidine series

PYRIMIDINE