ChemicalBook > CAS DataBase List > 4-Cyclohexylphenol

4-Cyclohexylphenol

Product Name
4-Cyclohexylphenol
CAS No.
1131-60-8
Chemical Name
4-Cyclohexylphenol
Synonyms
CYCLOHEXYL PHENOL;4-Cyclohexyphenol;4-cyclohexyl-pheno;P-CYCLOHEXYLPHENOL;4-CYCLOHEXYLPHENOL;Of cyclohexyl phenol;CYCLOHEXYLPHENOL, 4-;Phenol, p-cyclohexyl-;PARA-CYCLOHEXYLPHENOL;Phenol, 4-cyclohexyl-
CBNumber
CB9764431
Molecular Formula
C12H16O
Formula Weight
176.25
MOL File
1131-60-8.mol
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4-Cyclohexylphenol Property

Melting point:
130-135°C
Boiling point:
213-215°C
Density 
0.9452 (rough estimate)
vapor pressure 
0.823-3.6Pa at 25℃
refractive index 
1.5415 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
form 
Solid:flakes
pka
10.15±0.13(Predicted)
color 
White to Light yellow to Light orange
Water Solubility 
66.66mg/L(25 ºC)
Dielectric constant
4.0（54℃）
LogP
4.22-4.33
CAS DataBase Reference
1131-60-8(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-cyclohexyl-(1131-60-8)
EPA Substance Registry System
Phenol, 4-cyclohexyl- (1131-60-8)
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Safety

Hazard Codes 
Xi,N
Risk Statements 
20/21/22-36/37/38-50/53-41-37/38
Safety Statements 
26-36/37/39-61-60-39
Hazard Note 
Irritant
HS Code 
2907199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C0733
Product name
4-Cyclohexylphenol
Purity
>98.0%(GC)
Packaging
25g
Price
$182
Updated
2024/03/01
TRC
Product number
C992295
Product name
4-Cyclohexylphenol
Packaging
5g
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC149862
Product name
4-Cyclohexylphenol
Packaging
5G
Price
$62.5
Updated
2021/12/16
SynQuest Laboratories
Product number
2701-1-X8
Product name
4-Cyclohexylphenol
Purity
97%
Packaging
25g
Price
$32
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC149862
Product name
4-Cyclohexylphenol
Packaging
2g
Price
$50
Updated
2021/12/16
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4-Cyclohexylphenol Chemical Properties,Usage,Production

Uses

4-Cyclohexylphenol is a derivative of Cyclohexylphenol (CHP), which is widely used in the preparation of dyes, resins, and biocides[2]. 4-Cyclohexylphenol labelled with 35s can be used for metabolic studies[3].

Synthesis

4-Cyclohexylphenol is obtained by hydroalkylation of phenol using phenol as a raw material in the presence of a palladium catalyst and a molten salt (NaCl-AlCl3)[1]. The specific synthesis steps are as follows:
The hydroalkylation of phenol in the presence of palladium catalyst and fused salt (NaCl-AlCl3) under hydrogen pressure was carried out. By using 1% Pd-Al2O3 (1 g) and the fused salt (1 : 1 mol ratio, 6 g), 4-cyclohexylphenol was obtained selectively from 1 (30 g) in a yield of 31.9% at 120°C for 4.5 h.

References

[1] T. KAMIYAMA; M. I; S Enomoto. Hydroalkylation of phenol to cyclohexylphenol in the presence of Pd-Al2O3 and NaCl-AlCl3 under hydrogen pressure.[J]. Chemical & pharmaceutical bulletin, 1986. DOI:10.1248/CPB.34.450.
[2] S. GUTIéRREZ-RUBIO . Synthesis of cyclohexylphenol via phenol hydroalkylation using Co2P/zeolite catalysts[J]. Catalysis Today, 2022. DOI:10.1016/j.cattod.2021.11.039.
[3] D.J. HEARSE; Gillian M P; A H Olavesen. The preparation and characterization of a series of 35S-labelled aryl sulphate esters for metabolic studies[J]. Biochemical pharmacology, 1969. DOI:10.1016/0006-2952(69)90022-7.

4-Cyclohexylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Cyclohexylphenol Suppliers

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View Lastest Price from 4-Cyclohexylphenol manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-Cyclohexylphenol 1131-60-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-16
Hebei Guanlang Biotechnology Co,.LTD
Product
4-Cyclohexylphenol 1131-60-8
Price
US $54.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2021-07-12
Xingtai Haoxun Import and Export Trade Co., Ltd.
Product
4-Cyclohexylphenol 1131-60-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10tons
Release date
2020-07-14

1131-60-8, 4-CyclohexylphenolRelated Search:

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  • Phenol, p-cyclohexyl-
  • p-Hydroxyphenylcyclohexane
  • CYCLOHEXYL PHENOL
  • 4-cyclohexyl-pheno
  • 4-HYDROXYPHENYLCYCLOHEXANE
  • 4-CYCLOHEXYLPHENOL
  • P-CYCLOHEXYLPHENOL
  • CYCLOHEXYLPHENOL, 4-
  • PARA-CYCLOHEXYLPHENOL
  • 4-(Cyclohexane-1-yl)phenol
  • Of cyclohexyl phenol
  • 4-Cyclohexylphenol, >=97%
  • 4-Cyclohexylphenol &gt
  • Phenol, 4-cyclohexyl-
  • 4-Cyclohexyphenol
  • 1131-60-8
  • C12H16O
  • Aromatic Phenols