4-Cyclohexylphenol

Product Name: 4-Cyclohexylphenol
CAS No.: 1131-60-8
Chemical Name: 4-Cyclohexylphenol
Synonyms: CYCLOHEXYL PHENOL;4-Cyclohexyphenol;4-cyclohexyl-pheno;P-CYCLOHEXYLPHENOL;4-CYCLOHEXYLPHENOL;Of cyclohexyl phenol;CYCLOHEXYLPHENOL, 4-;Phenol, p-cyclohexyl-;PARA-CYCLOHEXYLPHENOL;Phenol, 4-cyclohexyl-
CBNumber: CB9764431
Molecular Formula: C12H16O
Formula Weight: 176.25
MOL File: 1131-60-8.mol

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4-Cyclohexylphenol Property

Melting point:: 130-135°C
Boiling point:: 213-215°C
Density: 0.9452 (rough estimate)
vapor pressure: 0.823-3.6Pa at 25℃
refractive index: 1.5415 (estimate)
storage temp.: Inert atmosphere,Room Temperature
form: Solid:flakes
pka: 10.15±0.13(Predicted)
color: White to Light yellow to Light orange
Water Solubility: 66.66mg/L(25 ºC)
Dielectric constant: 4.0（54℃）
LogP: 4.22-4.33
CAS DataBase Reference: 1131-60-8(CAS DataBase Reference)
NIST Chemistry Reference: Phenol, 4-cyclohexyl-(1131-60-8)
EPA Substance Registry System: Phenol, 4-cyclohexyl- (1131-60-8)

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Safety

Hazard Codes: Xi,N
Risk Statements: 20/21/22-36/37/38-50/53-41-37/38
Safety Statements: 26-36/37/39-61-60-39
Hazard Note: Irritant
HS Code: 2907199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C0733
Product name: 4-Cyclohexylphenol
Purity: >98.0%(GC)
Packaging: 25g
Price: $182
Updated: 2024/03/01

TRC

Product number: C992295
Product name: 4-Cyclohexylphenol
Packaging: 5g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC149862
Product name: 4-Cyclohexylphenol
Packaging: 5G
Price: $62.5
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2701-1-X8
Product name: 4-Cyclohexylphenol
Purity: 97%
Packaging: 25g
Price: $32
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC149862
Product name: 4-Cyclohexylphenol
Packaging: 2g
Price: $50
Updated: 2021/12/16

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4-Cyclohexylphenol Chemical Properties,Usage,Production

Uses

4-Cyclohexylphenol is a derivative of Cyclohexylphenol (CHP), which is widely used in the preparation of dyes, resins, and biocides^[2]. 4-Cyclohexylphenol labelled with 35s can be used for metabolic studies^[3].

Synthesis

4-Cyclohexylphenol is obtained by hydroalkylation of phenol using phenol as a raw material in the presence of a palladium catalyst and a molten salt (NaCl-AlCl3)^[1]. The specific synthesis steps are as follows:
The hydroalkylation of phenol in the presence of palladium catalyst and fused salt (NaCl-AlCl3) under hydrogen pressure was carried out. By using 1% Pd-Al2O3 (1 g) and the fused salt (1 : 1 mol ratio, 6 g), 4-cyclohexylphenol was obtained selectively from 1 (30 g) in a yield of 31.9% at 120°C for 4.5 h.

References

[1] T. KAMIYAMA; M. I; S Enomoto. Hydroalkylation of phenol to cyclohexylphenol in the presence of Pd-Al2O3 and NaCl-AlCl3 under hydrogen pressure.[J]. Chemical & pharmaceutical bulletin, 1986. DOI:10.1248/CPB.34.450.
[2] S. GUTIéRREZ-RUBIO . Synthesis of cyclohexylphenol via phenol hydroalkylation using Co2P/zeolite catalysts[J]. Catalysis Today, 2022. DOI:10.1016/j.cattod.2021.11.039.
[3] D.J. HEARSE; Gillian M P; A H Olavesen. The preparation and characterization of a series of 35S-labelled aryl sulphate esters for metabolic studies[J]. Biochemical pharmacology, 1969. DOI:10.1016/0006-2952(69)90022-7.

4-Cyclohexylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Cyclohexylphenol Suppliers

Americas 1 Austria 2 China 153 Europe 3 Germany 3 India 5 Japan 2 Norway 1 Ukraine 1 United Kingdom 11 United States 31 Global 213

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd

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J & K SCIENTIFIC LTD.

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TAIYUAN RHF CO.,LTD.

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Beijing Ouhe Technology Co., Ltd

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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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View Lastest Price from 4-Cyclohexylphenol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Cyclohexylphenol 1131-60-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KG
Release date: 2024-11-10

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Cyclohexylphenol 1131-60-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-16

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Cyclohexylphenol 1131-60-8
Price: US $54.60/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000kg
Release date: 2024-08-20

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4-cyclohexyl-pheno

4-HYDROXYPHENYLCYCLOHEXANE

4-CYCLOHEXYLPHENOL

P-CYCLOHEXYLPHENOL

CYCLOHEXYLPHENOL, 4-

PARA-CYCLOHEXYLPHENOL

4-(Cyclohexane-1-yl)phenol

Of cyclohexyl phenol

4-Cyclohexylphenol, >=97%

4-Cyclohexylphenol &gt

Phenol, 4-cyclohexyl-

4-Cyclohexyphenol

1131-60-8

C12H16O

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