HEPES sodium salt
- Product Name
- HEPES sodium salt
- CAS No.
- 75277-39-3
- Chemical Name
- HEPES sodium salt
- Synonyms
- HEPES NA;HEPES SODIUM SALT BUFFER;H7006-500G;(HEPES)2-NA;HEPES, SODIUM;HEPES NA-SALT;RUTHENIUM STAND;HEPES LOWSODIUM;HEPES SODIUM SALT;1.0 M HEPES sodium
- CBNumber
- CB9773992
- Molecular Formula
- C8H19N2NaO4S
- Formula Weight
- 262.3
- MOL File
- 75277-39-3.mol
HEPES sodium salt Property
- Melting point:
- 234 °C
- Density
- 1.504[at 20℃]
- vapor pressure
- 0Pa at 25℃
- storage temp.
- room temp
- solubility
- H2O: 1 M at 20 °C, clear, colorless
- form
- dry powder
- color
- White
- PH Range
- 6.8 - 8.2
- PH
- 10.0-12.0 (1M in H2O)
- pka
- 7.5(at 25℃)
- biological source
- synthetic
- Water Solubility
- It is soluble in water.
- Sensitive
- Hygroscopic
- Stability:
- Stable. Hygroscopic - protect from moisture. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 75277-39-3(CAS DataBase Reference)
- EPA Substance Registry System
- 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt (75277-39-3)
- Absorption
- ≤0.2 at 260 in H2O at 1M
≤0.2 at 280 in H2O at 1M
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- RES6007H-A7
- Product name
- HEPES sodium salt
- Packaging
- 1kg
- Price
- $1141
- Updated
- 2025/07/31
- Product number
- RES6007H-A7
- Product name
- HEPES sodium salt
- Packaging
- 25kg
- Price
- $14299
- Updated
- 2025/07/31
- Product number
- 391333
- Product name
- HEPES, Sodium Salt, ULTROL® Grade
- Purity
- A zwitterionic N-substituted aminosulfonic acid buffer. Useful in the pH 6.8-8.2 range. Has a pKa of 7.55 at 25°C. Absorbance (1.0 mM, H2O, 260 nm):0.10.
- Packaging
- 100G
- Price
- $166
- Updated
- 2025/07/31
- Product number
- 391333
- Product name
- HEPES, Sodium Salt, ULTROL® Grade
- Purity
- A zwitterionic N-substituted aminosulfonic acid buffer. Useful in the pH 6.8-8.2 range. Has a pKa of 7.55 at 25°C. Absorbance (1.0 mM, H2O, 260 nm):0.10.
- Packaging
- 500G
- Price
- $590
- Updated
- 2025/07/31
- Product number
- 391333
- Product name
- HEPES, Sodium Salt, ULTROL® Grade
- Purity
- A zwitterionic N-substituted aminosulfonic acid buffer. Useful in the pH 6.8-8.2 range. Has a pKa of 7.55 at 25°C. Absorbance (1.0 mM, H2O, 260 nm):0.10.
- Packaging
- 1KG
- Price
- $900
- Updated
- 2025/07/31
HEPES sodium salt Chemical Properties,Usage,Production
Chemical Properties
white powder
Uses
HEPES sodium salt solution is suitable for cell culture studies. It may be used in the preparation of buffer solution of HEPES. It may be used as buffer during the phosphorylation assays in permeabilized fibroblasts. It may be used to compose a complex dialysis buffer, used in the determination of free thyroxin in serum by radioimmunoassay.
Definition
ChEBI: Sodium 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate is an organic sodium salt, a N-(2-hydroxyethyl)piperazine and a N-(sulfoalkyl)piperazine. It contains a 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonate.
General Description
HEPES is a general-purpose zwitterionic buffer which does not bind magnesium, calcium, manganese(II) or copper(II) ions. HEPES has been classified as Good′s buffer by Dr. Norman Good and his colleagues in 1966. It is zwitterionic at biological pH and is most effective in the pH range of 6.8 to 8.2.
Flammability and Explosibility
Not classified
Biological Activity
Multi purpose buffer used in biological research.
Synthesis
103-76-4
1562-00-1
75277-39-3
The general procedure for the synthesis of N-(2-hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid) sodium salt from N-hydroxyethylpiperazine and sodium 2-hydroxyethanesulfonate is as follows: magnetic stirring in a 70-mL fluoropolymer-lined steel autoclave equipped with internal thermocouples for monitoring the temperature of the liquid phase, a pressure gauge, a pressure-reducing valve, and an exhaust valve. First, amine feedstock, anhydrous or aqueous sodium 2-hydroxyethanesulfonate solution, and anhydrous or aqueous sodium hydroxide solution were added to the open-topped autoclave. Subsequently, the autoclave was assembled and immersed in an electrically heated oil bath. The stirred reaction mixture was rapidly heated to the specified reaction temperature with the exhaust valve closed and maintained at that temperature for the time specified in Examples 9, 10 and 13. Upon completion of the reaction, the mixture was cooled to room temperature, the reactor was opened, and the reaction product was dissolved in a sufficient amount of water to ensure complete dissolution of all solids.
storage
Room temperature
References
[1] Patent: US2006/89509, 2006, A1. Location in patent: Page/Page column 4-6
[2] Patent: US2006/89509, 2006, A1. Location in patent: Page/Page column 4-6
HEPES sodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from HEPES sodium salt manufacturers
- Product
- HEPES sodium salt 75277-39-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- HEPES sodium salt 75277-39-3
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.8%
- Supply Ability
- 100tons
- Release date
- 2024-08-16
- Product
- HEPES NA 75277-39-3
- Price
- US $0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.5%
- Supply Ability
- 1000tons
- Release date
- 2023-09-14