Tidutamab

Product Name: Tidutamab
CAS No.: 2148354-90-7
Chemical Name: Tidutamab
Synonyms: Tidutamab;Research Grade Tidutamab;Research Grade Tidutamab (DHD91601)
CBNumber: CB98081145
Formula Weight: 0
MOL File: Mol file

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

Tidutamab Chemical Properties,Usage,Production

Uses

Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and T-cell binding domain (CD3). Tidutamab possesses a full Fc domain to maintain long serum half-life.Tidutamab eliminates SSTR+ tumor cells by stimulating redirected T cellmediated cytotoxicity (RTcC)[1].

in vivo

Tidutamab (XmAb-18087; 3 mg/kg; i.p.; single dose) stimulates human T cell killing of SSTR2+ A549 lung carcinoma tumors in NSG mice^[1].

Animal Model:	NSG mice^[1]
Dosage:	3 mg/kg
Administration:	Intraperitoneal injection; single dose
Result:	lnduced anti-tumor activity in human PBMC-engrafted NSG mice.

References

[1] Hyung LS, et, al. Anti-SSTR2 × anti-CD3 bispecific antibody induces potent killing of human tumor cells?in vitro?and in mice, and stimulates target-dependent T cell activation in monkeys: A potential immunotherapy for neuroendocrine tumors. Cancer Res?(2017) 77 (13_Supplement): 3633.

Tidutamab Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Tidutamab Suppliers

China 12 United States 1 Global 13

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Wuhan Chemstan Biotechnology Co., Ltd.

Tel: 027-65317797 15926423062
Fax: QQ：422450190
Email: 422450190@qq.com
Country: China
ProdList: 10308
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Biolab Reagents

Tel: 027-65279366 18108604356
Email: products@biolabreagent.com
Country: China
ProdList: 9868
Advantage: 58

Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 086-15871494362 13720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 6762
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Changsha Fuzhen Biotechnology Co.，LTD

Tel: 0731-13823398 15111215862
Email: 313359644@qq.com
Country: China
ProdList: 4161
Advantage: 58

Atagenix Laboratories

Tel: 027-87008169 17762441161
Email: info@atagenix.com
Country: China
ProdList: 10001
Advantage: 58

AntibodySystem Laboratories SAS

Tel: 33175446423
Email: support@antibodysystem.com
Country: China
ProdList: 6739
Advantage: 58

2148354-90-7, TidutamabRelated Search:

Porgaviximab Galegenimab Dezamizumab Lilotomab elsilimomab Olendalizumab Sotevtamab Zuberitamab Lulizumab Pegol Adintrevimab

Tidutamab

Research Grade Tidutamab (DHD91601)

Research Grade Tidutamab

2148354-90-7