7-FLUORO INDAZOLE
Uses- Product Name
- 7-FLUORO INDAZOLE
- CAS No.
- 341-24-2
- Chemical Name
- 7-FLUORO INDAZOLE
- Synonyms
- 7-FLUORO INDAZOLE;7-Fluoro-1H-indazole;1H-Indazole, 7-fluoro-;7-fluoro-1(2)H-indazole
- CBNumber
- CB9820894
- Molecular Formula
- C7H5FN2
- Formula Weight
- 136.13
- MOL File
- 341-24-2.mol
7-FLUORO INDAZOLE Property
- Melting point:
- 120 °C (decomp)
- Boiling point:
- 274.9±13.0 °C(Predicted)
- Density
- 1.370±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 12.10±0.40(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F595488
- Product name
- 7-Fluoro-1H-indazole
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- PC201233
- Product name
- 7-Fluoro-1H-indazole
- Purity
- 98%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- 3H32-3-49
- Product name
- 7-Fluoro-1H-indazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
- Product number
- PC201233
- Product name
- 7-Fluoro-1H-indazole
- Purity
- 98%
- Packaging
- 5g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- PC201233
- Product name
- 7-Fluoro-1H-indazole
- Purity
- 98%
- Packaging
- 10g
- Price
- $57
- Updated
- 2021/12/16
7-FLUORO INDAZOLE Chemical Properties,Usage,Production
Uses
7-Fluoro-1H-indazole is a heterocyclic organic compound that can be used as a pharmaceutical intermediate.
Synthesis
2646-91-5
341-24-2
General procedure for the synthesis of 7-fluoro-1H-indazole from 2,3-difluorobenzaldehyde: To 2,3-difluorobenzaldehyde (1.85 g) was added hydrazine monohydrate (3 ml), and the reaction mixture was heated with stirring at 180°C for 10 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted by adding ethyl acetate and water to separate the organic layer. The organic layer was washed with saturated brine, dried over anhydrous sodium sulfate and subsequently evaporated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography to afford 7-fluoro-1H-indazole (790 mg, 45% yield) using chloroform/acetone as eluent. The structure of the product was confirmed by 1H-NMR (CD3OD, 400 MHz): δ 7.08-7.12 (m, 2H), 7.56-7.59 (m, 1H), 8.10 (d, J = 3.4 Hz, 1H).
References
[1] Patent: EP1870414, 2007, A1. Location in patent: Page/Page column 23
[2] Patent: EP2752410, 2014, A1. Location in patent: Paragraph 0626
7-FLUORO INDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-FLUORO INDAZOLE manufacturers
- Product
- 7-FLUORO INDAZOLE 341-24-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 7-FLUORO INDAZOLE 341-24-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 7-FLUORO INDAZOLE 341-24-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-01