ChemicalBook > CAS DataBase List > Hydroxysafflor yellow A

Hydroxysafflor yellow A

Product Name
Hydroxysafflor yellow A
CAS No.
78281-02-4
Chemical Name
Hydroxysafflor yellow A
Synonyms
HSYA;SAFFLOMIN A;Hydroxysafflor yellow;Hydroxysafflor yellow A;Hydroxysafflor yellow A-RM;Hydroxy safflower yellow pigment A;Hydroxylsafflower yellow pigment A;Hydroxysafflor yellow A,Safflomin A;Hydroxysafflor yellow A,SaffloMin A,HSYA;Safflomin A, 98%, from Carthamus tinctorius L.
CBNumber
CB9843710
Molecular Formula
C27H32O16
Formula Weight
612.54
MOL File
78281-02-4.mol
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Hydroxysafflor yellow A Property

Melting point:
184-186 °C
Boiling point:
1015.8±65.0 °C(Predicted)
Density 
1.851±0.06 g/cm3(Predicted)
solubility 
DMF: 1 mg/ml; DMSO: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
pka
4.50±1.00(Predicted)
form 
powder
color 
Yellow-orange
LogP
1.688 (est)
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Safety

Safety Statements 
24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
300905
Product name
Safflomin A
Packaging
20mg
Price
$405
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259580
Product name
Safflomin A
Purity
98%
Packaging
20mg
Price
$408
Updated
2021/12/16
Matrix Scientific
Product number
097908
Product name
Hydroxysafflor yellow A
Purity
95+%
Packaging
250mg
Price
$431
Updated
2021/12/16
Biosynth Carbosynth
Product number
OH08134
Product name
Hydroxysafflor yellow A
Packaging
10mg
Price
$75
Updated
2021/12/16
Biorbyt Ltd
Product number
orb259580
Product name
Safflomin A
Purity
98%
Packaging
100mg
Price
$472.6
Updated
2021/12/16
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Hydroxysafflor yellow A Chemical Properties,Usage,Production

Definition

ChEBI: Hydroxysafflor yellow A is a C-glycosyl compound that is 3,4,5-trihydroxycyclohexa-2,5-dien-1-one which is substituted by beta-D-glucosyl groups at positions 2 and 4, and by a p-hydroxycinnamoyl group at position 6. It is the main bioactive compound of a traditional Chinese medicine obtained from safflower (Carthamus tinctorius). It has a role as an anti-inflammatory agent, an antioxidant, a platelet aggregation inhibitor, an antineoplastic agent, a radical scavenger, an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor, a neuroprotective agent and a plant metabolite. It is a C-glycosyl compound, a member of phenols, an enone and an enol.

Biological Activity

Hydroxysafflor yellow A is a pigment that has been found in C. tinctorius and has diverse biological activities. It inhibits LPS-induced increases in NF-κB levels and production of nitric oxide (NO), IL-1β, and TNF-α in primary mouse embryonic mesencephalic cultures when used at concentrations of 40 and 160 μM.

in vivo

Hydroxysafflor yellow A (1 and 3 mg/kg) decreases mean arterial pressure (MAP) and heart rate in anesthetized normotensive or spontaneously hypertensive rats. It reduces infarct volume and serum superoxide dismutase (SOD) activity in a rat model of focal transient cerebral is chemia induced by middle cerebral artery occlusion (MCAO) when administered at doses of 2, 4, and 8 mg/kg.

Hydroxysafflor yellow A Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Hydroxysafflor yellow A manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Hydroxysafflor yellow A 78281-02-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-10-12
Career Henan Chemical Co
Product
SAFFLOMIN A 78281-02-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

78281-02-4, Hydroxysafflor yellow ARelated Search:

Epmedin B Gallic acid monohydrate CALYCOSIN Isoalantolactone lithospermic acid Isoimperatorin AURANTIO-OBTUSIN Coumalic acid Cynaroside ARTEMISININ Gentiopicroside Resveratrol Linarin Schisandrin A Albiflorin FORSYTHIN Phloretin SAFFLOWER YELLOW

  • SAFFLOMIN A
  • Hydroxysafflor yellow A
  • 2,5-Cyclohexadien-1-one, 2,4-di-beta-D-glucopyranosyl-3,4,5-trihydroxy-6-((2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl)-
  • Hydroxysafflor yellow A,SaffloMin A,HSYA
  • Hydroxysafflor yellow A,Safflomin A
  • Hydroxysafflor yellow
  • Safflomin A, 98%, from Carthamus tinctorius L.
  • HSYA
  • 2,5-Cyclohexadien-1-one, 2,4-di-β-D-glucopyranosyl-3,4,5-trihydroxy-6-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-
  • 3,4,5-Trihydroxy-2-((E)-3-(4-hydroxyphenyl)acryloyl)-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-6-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)cyclohexa-2,5-dien-1-one
  • Hydroxy safflower yellow pigment A
  • Hydroxylsafflower yellow pigment A
  • Hydroxysafflor yellow A-RM
  • 78281-02-4
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract