ChemicalBook > CAS DataBase List > 7-BROMO-4-CHLOROQUINAZOLINE
7-BROMO-4-CHLOROQUINAZOLINE
- Product Name
- 7-BROMO-4-CHLOROQUINAZOLINE
- CAS No.
- 573675-55-5
- Chemical Name
- 7-BROMO-4-CHLOROQUINAZOLINE
- Synonyms
- 7-Bromo-4-chloro-quizoline;7-BROMO-4-CHLOROQUINAZOLINE;7-BroMo-4-chloroquinazoli...;Quinazoline, 7-bromo-4-chloro-
- CBNumber
- CB9846726
- Molecular Formula
- C8H4BrClN2
- Formula Weight
- 243.49
- MOL File
- 573675-55-5.mol
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7-BROMO-4-CHLOROQUINAZOLINE Property
- Boiling point:
- 339.7±22.0 °C(Predicted)
- Density
- 1.762±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.09±0.30(Predicted)
- Appearance
- Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- B415553
- Product name
- 7-Bromo-4-chloroquinazoline
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB42265
- Product name
- 7-Bromo-4-chloroquinazoline
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 3H32-D-31
- Product name
- 7-Bromo-4-chloroquinazoline
- Packaging
- 250mg
- Price
- $104
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB42265
- Product name
- 7-Bromo-4-chloroquinazoline
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB42265
- Product name
- 7-Bromo-4-chloroquinazoline
- Packaging
- 500mg
- Price
- $150
- Updated
- 2021/12/16
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7-BROMO-4-CHLOROQUINAZOLINE Chemical Properties,Usage,Production
Synthesis
194851-16-6
573675-55-5
General procedure for the synthesis of 7-bromo-4-chloroquinazoline from 7-bromo-3,4-dihydroquinazolin-4-one: 20.4 mL (0.12 mol) of N-ethyl diisopropylamine was added slowly and dropwise to 55.0 g (0.24 mol) of 7-bromo-3H-quinazolin-4-one suspended in 300 mL of phosphorus trichloride. The reaction mixture was stirred at 115 °C for 3 hours and subsequently cooled to room temperature. After conventional post-processing, 48.0 g of the target product 7-bromo-4-chloroquinazoline was obtained as a solid as confirmed by HPLC/MS analysis ([M+H]+ = 244).
References
[1] Patent: US2013/12489, 2013, A1. Location in patent: Paragraph 0183
[2] Patent: WO2010/146173, 2010, A1. Location in patent: Page/Page column 16-17
[3] Patent: WO2005/42498, 2005, A2. Location in patent: Page/Page column 43
[4] Chemical Biology and Drug Design, 2018, vol. 92, # 5, p. 1859 - 1866
7-BROMO-4-CHLOROQUINAZOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-BROMO-4-CHLOROQUINAZOLINE manufacturers
Career Henan Chemical Co
- Product
- 7-BROMO-4-CHLOROQUINAZOLINE 573675-55-5
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08
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