3-Hydroxyphenylacetylene

Product Name: 3-Hydroxyphenylacetylene
CAS No.: 10401-11-3
Chemical Name: 3-Hydroxyphenylacetylene
Synonyms: 3-ETHYNYLPHENOL;4-ETHYNYL-PHENOL;Phenol, 3-ethynyl-;TIMTEC-BB SBB005886;3-HYDROXYPHENYLACETYLENE;Phenol, 3-ethynyl- (9CI);M-HYDROXYPHENYLACETYLENE;3-HYDROXYPHENYLACETYLENE, 95+%;3-Hydroxyphenylacetylene >=95.0%;3-HYDROXYPHENYLACETYLENE (3-Ethynylphenol)
CBNumber: CB9852635
Molecular Formula: C8H6O
Formula Weight: 118.13
MOL File: 10401-11-3.mol

More

Less

3-Hydroxyphenylacetylene Property

Melting point:: 64-66 °C
Boiling point:: 75°C 3mm
Density: 1.083 g/mL at 25 °C(lit.)
refractive index: n20/D 1.5840(lit.)
Flash point:: 218 °F
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Miscible with dimethylformamide.
pka: 9.30±0.10(Predicted)
form: Crystalline Powder
color: White to pale yellow
BRN: 2076613
InChI: InChI=1S/C8H6O/c1-2-7-4-3-5-8(9)6-7/h1,3-6,9H
InChIKey: AODMJIOEGCBUQL-UHFFFAOYSA-N
SMILES: C1(O)=CC=CC(C#C)=C1
CAS DataBase Reference: 10401-11-3(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-41-52/53
Safety Statements: 26-37/39
RIDADR: 2810
WGK Germany: 2
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29071990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 632023
Product name: 3-Hydroxyphenylacetylene
Purity: ≥95.0%
Packaging: 1g
Price: $66.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 632023
Product name: 3-Hydroxyphenylacetylene
Purity: ≥95.0%
Packaging: 5g
Price: $271
Updated: 2025/07/31

TCI Chemical

Product number: E1421
Product name: 3-Ethynylphenol
Purity: min. 98.0 %
Packaging: 1G
Price: $277
Updated: 2025/07/31

TRC

Product number: E938110
Product name: 3-Ethynylphenol
Packaging: 100mg
Price: $65
Updated: 2021/12/16

GFS CHEMICALS

Product number: 81992
Product name: 3-ETHYNYLPHENOL,95%
Packaging: 10g
Price: $777.23
Updated: 2021/12/16

More

Less

3-Hydroxyphenylacetylene Chemical Properties,Usage,Production

Chemical Properties

Clear yellow liquid

Uses

3-Hydroxyphenylacetylene is used as a fluorogenic and chromogenic probe for bacterial enzymes.

Synthesis

388061-72-1

10401-11-3

The general procedure for the synthesis of 3-hydroxyphenylacetylene from (3-hydroxyphenylalkynyl)trimethylsilane was as follows: (3-hydroxyphenylalkynyl)trimethylsilane was dissolved in a mixed solvent of THF (6 mL) and MeOH (6 mL), followed by the addition of 10% aqueous KOH solution (6 mL). The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction mixture was neutralized with 1N HCl solution and the solvent was subsequently removed by rotary evaporation. The aqueous phase was extracted with CH2Cl2 and the organic phase was dried with anhydrous Na2SO4. Finally, purification by column chromatography (eluent: n-hexane/acetone, 5:1, v/v) afforded 3-hydroxyphenylacetylene (162.8 mg, 70% yield), the product was a yellow oil.

References

[1] Patent: US2009/68242, 2009, A1. Location in patent: Page/Page column 7
[2] Organic Letters, 2014, vol. 16, # 24, p. 6302 - 6305

3-Hydroxyphenylacetylene Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Hydroxyphenylacetylene Suppliers

Americas 1 Belgium 1 Canada 2 China 130 Europe 3 Germany 3 India 12 Japan 1 Switzerland 3 United Kingdom 4 United States 27 Global 187

Shanghai Puhao Chemical Technology Co. Ltd.

Tel: 13761817188
Email: 774028079@qq.com
Country: China
ProdList: 291
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Jinan Trio PharmaTech Co., Ltd.

Tel: 0531-88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com
Country: China
ProdList: 1856
Advantage: 62

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

More

Less

View Lastest Price from 3-Hydroxyphenylacetylene manufacturers

Career Henan Chemical Co

Product: 3-Hydroxyphenylacetylene 10401-11-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

10401-11-3, 3-HydroxyphenylacetyleneRelated Search:

3-ETHYNYLANISOLE 96 fenleuton 3-Hydroxyphenylacetylene 3',4'-DIMETHOXYPHENYL ACETYLENE 1-ETHYNYL-3 5-DIMETHOXYBENZENE 98 5-[(4-METHOXYPHENYL)ETHYNYL]-1,3-BENZODIOXOLE 1,4-diethynyl-2,5-dimethoxybenzene Rooperol 3-(DIFLUOROMETHOXY)PHENYLACETYLENE 1-(2-(3-METHOXYPHENYL)ETHYNYL)BENZENE 1-TRIMETHYLSILYLETHYNYL-3 5-DIMETHOXYBE& 3-METHOXYPHENYLPROPARGYL ALCOHOL 3-((4-METHOXYPHENYL)ETHYNYL)PHENOL 2-ETHYNYL-PHENOL 2,6-DI-TERT-BUTYL-4-ETHYNYL-PHENOL 4-ETHYNYL-PHENOL SALOR-INT L162515-1EA 2-METHOXY-4-(5-MORPHOLIN-4-YLPENTA-1,3-DIYNYL)PHENOL HYDROCHLORIDE

3-ETHYNYLPHENOL

3-HYDROXYPHENYLACETYLENE

4-ETHYNYL-PHENOL

TIMTEC-BB SBB005886

3-HYDROXYPHENYLACETYLENE (3-Ethynylphenol)

Phenol, 3-ethynyl- (9CI)

3-HYDROXYPHENYLACETYLENE, 95+%

M-HYDROXYPHENYLACETYLENE

Phenol, 3-ethynyl-

3-Ethynylphenol 3-Hydroxyphenylacetylene

3-Hydroxyphenylacetylene >=95.0%

3-ETHYNYLPHENOL, 95%3-ETHYNYLPHENOL, 95%3-ETHYNYLPHENOL, 95%

10401-11-3

HOC6H4CCH

ALCOHOL

Terminal

Organic Building Blocks

Alkynes

Building Blocks