3-Hydroxyphenylacetylene
- Product Name
- 3-Hydroxyphenylacetylene
- CAS No.
- 10401-11-3
- Chemical Name
- 3-Hydroxyphenylacetylene
- Synonyms
- 3-ETHYNYLPHENOL;4-ETHYNYL-PHENOL;Phenol, 3-ethynyl-;TIMTEC-BB SBB005886;3-HYDROXYPHENYLACETYLENE;Phenol, 3-ethynyl- (9CI);M-HYDROXYPHENYLACETYLENE;3-HYDROXYPHENYLACETYLENE, 95+%;3-Hydroxyphenylacetylene >=95.0%;3-HYDROXYPHENYLACETYLENE (3-Ethynylphenol)
- CBNumber
- CB9852635
- Molecular Formula
- C8H6O
- Formula Weight
- 118.13
- MOL File
- 10401-11-3.mol
3-Hydroxyphenylacetylene Property
- Melting point:
- 64-66 °C
- Boiling point:
- 75°C 3mm
- Density
- 1.083 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.5840(lit.)
- Flash point:
- 218 °F
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Miscible with dimethylformamide.
- pka
- 9.30±0.10(Predicted)
- form
- Crystalline Powder
- color
- White to pale yellow
- BRN
- 2076613
- InChI
- InChI=1S/C8H6O/c1-2-7-4-3-5-8(9)6-7/h1,3-6,9H
- InChIKey
- AODMJIOEGCBUQL-UHFFFAOYSA-N
- SMILES
- C1(O)=CC=CC(C#C)=C1
- CAS DataBase Reference
- 10401-11-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-41-52/53
- Safety Statements
- 26-37/39
- RIDADR
- 2810
- WGK Germany
- 2
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 29071990
N-Bromosuccinimide Price
- Product number
- 632023
- Product name
- 3-Hydroxyphenylacetylene
- Purity
- ≥95.0%
- Packaging
- 1g
- Price
- $66.6
- Updated
- 2025/07/31
- Product number
- 632023
- Product name
- 3-Hydroxyphenylacetylene
- Purity
- ≥95.0%
- Packaging
- 5g
- Price
- $271
- Updated
- 2025/07/31
- Product number
- E1421
- Product name
- 3-Ethynylphenol
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $277
- Updated
- 2025/07/31
- Product number
- 81992
- Product name
- 3-ETHYNYLPHENOL,95%
- Packaging
- 10g
- Price
- $777.23
- Updated
- 2021/12/16
- Product number
- E938110
- Product name
- 3-Ethynylphenol
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
3-Hydroxyphenylacetylene Chemical Properties,Usage,Production
Chemical Properties
Clear yellow liquid
Uses
3-Hydroxyphenylacetylene is used as a fluorogenic and chromogenic probe for bacterial enzymes.
Synthesis
388061-72-1
10401-11-3
The general procedure for the synthesis of 3-hydroxyphenylacetylene from (3-hydroxyphenylalkynyl)trimethylsilane was as follows: (3-hydroxyphenylalkynyl)trimethylsilane was dissolved in a mixed solvent of THF (6 mL) and MeOH (6 mL), followed by the addition of 10% aqueous KOH solution (6 mL). The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction mixture was neutralized with 1N HCl solution and the solvent was subsequently removed by rotary evaporation. The aqueous phase was extracted with CH2Cl2 and the organic phase was dried with anhydrous Na2SO4. Finally, purification by column chromatography (eluent: n-hexane/acetone, 5:1, v/v) afforded 3-hydroxyphenylacetylene (162.8 mg, 70% yield), the product was a yellow oil.
References
[1] Patent: US2009/68242, 2009, A1. Location in patent: Page/Page column 7
[2] Organic Letters, 2014, vol. 16, # 24, p. 6302 - 6305
3-Hydroxyphenylacetylene Preparation Products And Raw materials
Raw materials
Preparation Products
3-Hydroxyphenylacetylene Suppliers
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- Country
- Germany
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View Lastest Price from 3-Hydroxyphenylacetylene manufacturers
- Product
- 3-Hydroxyphenylacetylene 10401-11-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-09