Hoechst 33342
- Product Name
- Hoechst 33342
- CAS No.
- 23491-52-3
- Chemical Name
- Hoechst 33342
- Synonyms
- 33342;ho342;H33342;HOE 33342;Hoest 33342;Hoechst®HOECHST 33342;hoescht 33342;HOE-33342 3HCL;HOECHST NO 33342
- CBNumber
- CB9853364
- Molecular Formula
- C27H28N6O
- Formula Weight
- 452.55
- MOL File
- 23491-52-3.mol
Hoechst 33342 Property
- Boiling point:
- 725.9±70.0 °C(Predicted)
- Density
- 1.274±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble20mg/mL
- form
- Yellow solid
- pka
- 10.97±0.10(Predicted)
- color
- Brown to breen
- Water Solubility
- Water : 1 mg/mL (2.21 mM; ultrasonic and warming and heat to 80°C)
- BRN
- 1234011
- CAS DataBase Reference
- 23491-52-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,C
- Risk Statements
- 22-37/38-36/37/38-20/21/22-37-35
- Safety Statements
- 22-36/37-24/25-36-26-45-36/37/39
- WGK Germany
- 3
- RTECS
- DT4200000
- F
- 3-8-10
- HS Code
- 32129000
- Toxicity
- dni-hmn-hla 300 nmol/L CRNGDP 13,2389,1992
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 382065
- Product name
- Bisbenzimide H 33342 Fluorochrome, Trihydrochloride
- Purity
- Cell-permeable, adenine-thymine-specific fluorescent stain.
- Packaging
- 100mg
- Price
- $165
- Updated
- 2024/03/01
- Product number
- J62134
- Product name
- bis-Benzimide H-33342 trihydrochloride trihydrate, 98%
- Packaging
- 100mg
- Price
- $135
- Updated
- 2024/03/01
- Product number
- 5117
- Product name
- Hoechst33342
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $54
- Updated
- 2021/12/16
- Product number
- H456605
- Product name
- Hoechst33342
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 255461
- Product name
- Hoechst 33342
- Packaging
- 50mg
- Price
- $285
- Updated
- 2021/12/16
Hoechst 33342 Chemical Properties,Usage,Production
Chemical Properties
yellow powder
Uses
Hoechst 33342 is an A:T-specific DNA minor groove ligand that is a widely used fluorochrome for visualizing cellular DNA. Excitation of the dye occurs around 350 nm with an emission maxima around 461 nm. Hoechst-33342, unlike other Hoechst dyes, is more lipophillic due to an additional ethyl group. The compound has been observed to displace several known DNA intercalators. Adriamycin has been shown to disrupt the DNA dye update. The compound can be used in sorting living cells based on DNA content by FACS, in the visualization of chromatin distribution in living cells, to detect BrdU incorporation into cells, the visualization of fixed cells by microscopy, and to study the initial stages of apoptosis and cell-cycle distribution. In addition to Hoechst-33342''s fluorescent capability, the
Uses
Hoechst 33342 is useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry. Suitable for vital DNA staining of a variety of cell types and as a probe of membrane permeability in mammalian cells.
Definition
ChEBI: 2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole is a bibenzimidazole and a N-methylpiperazine. It has a role as a fluorochrome. It is functionally related to a pibenzimol.
Safety Profile
Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx.
Hoechst 33342 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Hoechst 33342 manufacturers
- Product
- Hoechst 33342 23491-52-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-09-28
- Product
- Hoechst 33342 23491-52-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 100kg
- Release date
- 2018-12-25