2-Aminobenzenesulfonamide
- Product Name
- 2-Aminobenzenesulfonamide
- CAS No.
- 3306-62-5
- Chemical Name
- 2-Aminobenzenesulfonamide
- Synonyms
- orthanilamide;o-sulfanilamide;2-Sulphamoylaniline;2-Aminobenzenesulfamide;2-Amino-benzenesulfomide;2-Aminobenzenesulfonamde;2-amino-benzenesulfonamid;o-aminobenzenesulfonamide;o-amino-benzenesulfonamid;2-AMINOBENZENESULFONAMIDE
- CBNumber
- CB9853506
- Molecular Formula
- C6H8N2O2S
- Formula Weight
- 172.2
- MOL File
- 3306-62-5.mol
2-Aminobenzenesulfonamide Property
- Melting point:
- 155-157 °C(lit.)
- Boiling point:
- 392.7±44.0 °C(Predicted)
- Density
- 1.3250 (rough estimate)
- refractive index
- 1.6490 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- pka
- 10.29±0.60(Predicted)
- form
- Solid
- color
- Off-White to Beige
- Water Solubility
- 6.655g/L(24 ºC)
- InChI
- InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
- InChIKey
- YAZSBRQTAHVVGE-UHFFFAOYSA-N
- SMILES
- C1(S(N)(=O)=O)=CC=CC=C1N
- CAS DataBase Reference
- 3306-62-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 36/37/39-26-22-36
- WGK Germany
- 3
- RTECS
- DA9449000
- Hazard Note
- Irritant
- HS Code
- 29350090
N-Bromosuccinimide Price
- Product number
- 245887
- Product name
- 2-Aminobenzenesulfonamide
- Purity
- 98%
- Packaging
- 5g
- Price
- $53.9
- Updated
- 2025/07/31
- Product number
- 245887
- Product name
- 2-Aminobenzenesulfonamide
- Purity
- 98%
- Packaging
- 25g
- Price
- $218
- Updated
- 2023/06/20
- Product number
- B401505
- Product name
- 2-Aminobenzenesulfonamide
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- OR27532
- Product name
- 2-Aminobenzenesulphonamide
- Purity
- 98%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 8669-1-X3
- Product name
- 2-Aminobenzenesulfonamide
- Packaging
- 1g
- Price
- $20
- Updated
- 2021/12/16
2-Aminobenzenesulfonamide Chemical Properties,Usage,Production
Chemical Properties
white to pale cream crystalline powder or crystals
Uses
Diuretic;Inhibitor of carbonic anhydrase B
Definition
ChEBI: 2-aminobenzenesulfonamide is a sulfonamide and a member of benzenes.
Synthesis
5455-59-4
3306-62-5
General procedure for the synthesis of o-aminobenzenesulfonamide from 2-nitrobenzenesulfonamide: 2-nitrobenzenesulfonamide (80.0 g, 0.58 mol) was dissolved in methanol in the presence of a Pd/C catalyst (10.0 g, 13% w/w) to prepare a solution with a mass concentration of 10%. The hydrogenation reaction was carried out at 50 psi hydrogen pressure and 60°C and the reaction was continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to give 60 g of off-white solid o-aminobenzenesulfonamide in 95% yield.
IC 50
CA Ⅸ
Solubility in organics
2-Aminobenzenesulfonamide is freely soluble in water, glacial acetic acid, ethyl alcohol, acetone, and methanol; insoluble in benzene.
References
[1] Patent: CN104761514, 2016, B. Location in patent: Paragraph 0028-0030
[2] Tetrahedron Letters, 2001, vol. 42, # 33, p. 5601 - 5603
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 7, p. 2455 - 2478
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 17, p. 5647 - 5647
[5] Bihang till Svenska Vet.-Akad. Handlingar, vol. 27, p. II, No. 1, S. 4
2-Aminobenzenesulfonamide Preparation Products And Raw materials
Raw materials
Preparation Products
2-Aminobenzenesulfonamide Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74
View Lastest Price from 2-Aminobenzenesulfonamide manufacturers
- Product
- 2-Aminobenzenesulfonamide 3306-62-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
- Product
- 2-Aminobenzenesulfonamide 3306-62-5
- Price
- US $522.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2018-07-23