ChemicalBook > CAS DataBase List > 2-Chloropropane

2-Chloropropane

Product Name
2-Chloropropane
CAS No.
75-29-6
Chemical Name
2-Chloropropane
Synonyms
ISOPROPYL CHLORIDE;2-CHLOROPROP-1-ENE;2-CHLORO-1-PROPENE;2-chloropropane(isopropylchloride);R280da;Isoprid;Narcosop;iso-C3H7Cl;2-Chlorpropan;2-CHLOROPROPANE
CBNumber
CB9854220
Molecular Formula
C3H7Cl
Formula Weight
78.54
MOL File
75-29-6.mol
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2-Chloropropane Property

Melting point:
-118 °C
Boiling point:
35 °C
Density 
0.859 g/mL at 25 °C(lit.)
vapor pressure 
28.11 psi ( 55 °C)
refractive index 
n20/D 1.395(lit.)
Flash point:
−31 °F
storage temp. 
Store below +30°C.
solubility 
alcohol: miscible(lit.)
form 
clear liquid
color 
Colorless to Light yellow
explosive limit
2.8-10.7%(V)
Water Solubility 
3.1 g/L (20 ºC)
Merck 
14,5211
BRN 
1730782
Stability:
Stable. Incompatible with strong oxidizing agents, strong bases. Highly flammable - note low flash point. Cool to zero C before opening.
CAS DataBase Reference
75-29-6(CAS DataBase Reference)
NIST Chemistry Reference
Propane, 2-chloro-(75-29-6)
EPA Substance Registry System
2-Chloropropane (75-29-6)
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Safety

Hazard Codes 
F+,Xi,Xn,F
Risk Statements 
12-36/37-20/21/22-11-40
Safety Statements 
9-29-36-26-16
RIDADR 
UN 2456 3/PG 1
WGK Germany 
3
RTECS 
UC7200000
F 
10-23
Autoignition Temperature
590 °C
TSCA 
Yes
HazardClass 
3
PackingGroup 
I
HS Code 
29031980
Hazardous Substances Data
75-29-6(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.02809
Product name
2-Chloropropane
Purity
for synthesis
Packaging
100mL
Price
$43.4
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02809
Product name
2-Chloropropane
Purity
for synthesis
Packaging
1L
Price
$97.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02809
Product name
2-Chloropropane
Purity
for synthesis
Packaging
2.5L
Price
$192
Updated
2024/03/01
Sigma-Aldrich
Product number
02489
Product name
2-Chloropropane
Purity
analytical standard
Packaging
5ml
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
240613
Product name
2-Chloropropane
Purity
≥99%
Packaging
100ml
Price
$49.8
Updated
2023/06/20
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2-Chloropropane Chemical Properties,Usage,Production

Chemical Properties

Colourless liquid

Uses

2-Chloropropane decomposes by first-order reaction to give hydrogen chloride and propylene. It is a short-chain chlorinated paraffins that is a component in lubricant additives, metal processing, leather fat-liquoring, plastics softening, PVC plasticizing, flame retardants in paints, adhesives and sealants. It shows anesthetic properties. Further, it is used as an alternative foam-blowing agent.
2-Chloropropane is used as a solvent and an intermediate.It can be used as a reactant:
In the Friedel-Crafts alkylation reaction of difluorobenzene and toluene using solid acid and methylalumoxane catalysts, respectively.
To prepare 4-amino-3-iodo-1-(isopropyl)pyrazolo[3,4-d]pyrimidine, a key intermediate for the synthesis of PfPK7 kinase inhibitors.
It is used to prepare benzylisopropylphenylphosphine and chlorodiethylisopropylsilane.

Uses

2-Chloropropane is used as a solvent and an intermediate. It shows anesthetic properties. Further, it is used as an alternative foam-blowing agent. It is used to prepare chlorodiethylisopropylsilane.

General Description

A colorless liquid with a chloroform-like odor. Vapors heavier than air. Less dense than water. May irritate skin and eyes, and be narcotic in high concentrations. A fire and explosion risk. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Slightly soluble in water.

Reactivity Profile

Halogenated aliphatic compounds, such as 2-Chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Hazard

Highly flammable, fire and explosion risk, explosive limits in air 2.8–10.7%.

Health Hazard

ACUTE/CHRONIC HAZARDS: Fire hazard: Highly dangerous; when exposed to heat, flame or oxidizers. Explosion hazard: Moderate when exposed to heat or flame.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mutation data reported. A flammable liquid. A very dangerous fire hazard when exposed to heat, flame, or oxidners. When heated to decomposition it emits toxic fumes of Cl-. See also 1 CHLOROPROPANE.

Purification Methods

Purify the chloride with 95% H2SO4 as described for isopropyl bromide, then dry with MgSO4, P2O5 or CaH2, and fractionally distil it from Na2CO3 or CaH2. Alternatively, a stream of oxygen containing ca 5% ozone is passed through the chloride for about three times as long as is necessary to obtain the first coloration of starch iodide paper by the exit gas, and the liquid is then washed with NaHCO3 solution to hydrolyse ozonides and remove organic acids before drying and distilling. [Beilstein 1 IV 191.]

2-Chloropropane Preparation Products And Raw materials

Raw materials

Anhydrous hydrogen chloride Montmorillonite K10 Zinc chloride Hydrochloric acid Isopropyl alcohol

Preparation Products

6-Methylnicotinaldehyde DISOPYRAMIDE 2,6-Dimethylbenzaldehyde Propoxur 3-methyl-4-propan-2-ylphenol 2-(4-CHLOROPHENYL)-3-METHYLBUTYRONITRILE 3-ISOPROPOXYANILINE 2-Pyridineboronic acid 2-(4-Chlorophenyl)-3-methylbutyric acid ISOPROPYLMAGNESIUM CHLORIDE Thymol 5-BROMO-3-METHYL-2-PYRIDINECARBALDEHYDE Thiazole-5-carboxylic acid Fenvalerate 5-Bromothiazole brofenvalerate 2-TRIFLUOROMETHYLQUINOLINE 2-Isopropoxyphenol 6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE Flutolanil Propachlor
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2-Chloropropane Suppliers

Americas 1 Belgium 3 Bulgaria 1 Canada 1 CHINA 240 Europe 1 France 3 Germany 9 India 32 Japan 10 Slovakia 1 Spain 1 Switzerland 3 Ukraine 2 United Kingdom 11 United States 33 Global 352
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View Lastest Price from 2-Chloropropane manufacturers

Hebei Miaoyin Technology Co.,Ltd
Product
2-Chloropropane 75-29-6
Price
US $20.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000
Release date
2023-04-14
Hebei Weibang Biotechnology Co., Ltd
Product
2-Chloropropane 75-29-6
Price
US $9.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-04
Hebei Yanxi Chemical Co., Ltd.
Product
2-Chloropropane 75-29-6
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-16

75-29-6, 2-ChloropropaneRelated Search:

Promethazine hydrochloride PROMETHAZINE 1,1,1,2,3,3,3-HEPTACHLOROPROPANE Calcium chloride p-Aminobenzylchloride Triisopropylsilyl chloride (-)-ISOPROTERENOL HYDROCHLORIDE Propane Propofol Resin epoxy Isopropyl acetate Sodium chloride Cinnamyl chloride ISOPROPYL LAURATE tert-Butyldimethylsilyl chloride Choline chloride Isopropyl alcohol Potassium chloride

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  • 2-chloro propane or 2-broMo propane
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  • Propane-2-chloro
  • R280da
  • sec-Propyl chloride
  • sec-propylchloride
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  • 2-Chloropropane, ≥ 99.0%
  • 2-Chloropropane (25%M in THF)
  • 75-29-6
  • 5-29-6
  • 557982
  • 75296
  • CH3CHClCH3
  • CH32CHCl
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  • Alkyl
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