ChemicalBook > CAS DataBase List > proquazone

proquazone

Product Name
proquazone
CAS No.
22760-18-5
Chemical Name
proquazone
Synonyms
43-715;Arthrex;Biarsan;Biarison;SaH-43-715;proquazone;Proquazona;Proquazonum;Sandoz-43-715;7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
CBNumber
CB9880256
Molecular Formula
C18H18N2O
Formula Weight
278.35
MOL File
22760-18-5.mol
More
Less

proquazone Property

Melting point:
137-138°
Boiling point:
436.12°C (rough estimate)
Density 
1.1707 (rough estimate)
refractive index 
1.5700 (estimate)
pka
0.74±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
P839145
Product name
Proquazone
Packaging
50mg
Price
$1100
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012353
Product name
PROQUAZONE
Purity
95.00%
Packaging
5MG
Price
$499.39
Updated
2021/12/16
More
Less

proquazone Chemical Properties,Usage,Production

Uses

Anti-inflammatory.

Uses

Proquazone is a non-steroidal anti-inflammatory drug.

Definition

ChEBI: Proquazone is a member of pyrimidines.

brand name

Arthrex (Novartis), Biarison (Swiss-Pharma, Egypt; Biochemie, Austria; ICN Alkaloida, Hungary; Sandoz, Finland, Turkey).

Clinical Use

Proquazone has been used successfully to treat rheumatoid polyarthritis. At 900 mg/d it is comparable in effect to 150 mg/d of indomethacin. Gastrointestinal disturbances are the principal adverse effects observed with its use.

Synthesis

Synthesis: proquazone is prepared by the alkylation of 2-amino-4-methylbenzophenone with 2-iodopropane in the presence of sodium carbonate to give 4-methyl-2-[(1- methylethyl)amino]benzophenone, which is condensed with urethane in the presence of zinc chloride at 190 ?C.

proquazone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

proquazone Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58

22760-18-5, proquazone Related Search:


  • 43-715
  • Biarison
  • Biarsan
  • SaH-43-715
  • Sandoz-43-715
  • 7-Methyl-1-(1-methylethyl)-4-phenyl-2(1H)-quinazolinone
  • proquazone
  • 2(1H)-Quinazolinone, 7-methyl-1-(1-methylethyl)-4-phenyl-
  • 7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
  • Arthrex
  • Proquazona
  • Proquazonum
  • 22760-18-5