3,4-Dihydroxy-5-Nitrobenzoic Acid Chemical Properties

Melting point:

>222oC (dec.)

Boiling point:

411.1±45.0 °C(Predicted)

Density 

1.799±0.06 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

3.82±0.10(Predicted)

color 

Yellow to Beige

3,4-Dihydroxy-5-Nitrobenzoic Acid Usage And Synthesis

Uses

3,4-Dihydroxy-5-nitrobenzoic Acid is a useful synthetic intermediate in the synthesis of Entacapone; a peripherally selective inhibitor of catechol-O-methyltransferase (COMT). Also an antiparkinsonian.

Uses

3,4-Dihydroxy-5-nitrobenzoic Acid is a useful synthetic intermediate in the synthesis of Entacapone (E558500); a peripherally selective inhibitor of catechol-O-methyltransferase (COMT). Also an antiparkinsonian.

3,4-Dihydroxy-5-Nitrobenzoic Acid(84211-30-3)Related Product Information

• (E/Z)-3-O-Methyl Entacapone
• CIS-ENTACAPONE
• (E)-3-O-Methyl Entacapone
• Entacapone
• (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
• (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
• TYRPHOSTIN AG 1290
• Entacapone EP IMpurity I
• 3,5-DINITROCATECHOL
• 3-Nitro-4,5-dihydroxybenzaldehyde
• 4-Aminobenzoic acid
• Sodium hydroxide
• Entacapone Impurity 4
• 6-Methoxy-2,4-dinitrophenol
• Entacapone 3-b-D-Glucuronide
• Entacapone Impurity 13
• 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N,N-diethyl-, (2E)-
• Entacapone Impurity 10