TYRPHOSTIN AG 1290 Chemical Properties

Boiling point:

478.9±45.0 °C(Predicted)

Density 

1.744±0.06 g/cm3(Predicted)

form 

Yellow to green solid.

pka

0.51±0.10(Predicted)

InChI

InChI=1S/C10H6N2O6/c11-4-6(10(15)16)1-5-2-7(12(17)18)9(14)8(13)3-5/h1-3,13-14H,(H,15,16)/b6-1+

InChIKey

XDDDOLQEZBJWFZ-LZCJLJQNSA-N

SMILES

C(O)(=O)/C(/C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1

TYRPHOSTIN AG 1290 Usage And Synthesis

Uses

Entacapone Acid, is the acid derivative of Entacapone (E558500). (E)-Isomer of Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.

TYRPHOSTIN AG 1290(160391-70-8)Related Product Information

• (E/Z)-3-O-Methyl Entacapone
• Entacapone EP IMpurity I
• 3-Nitro-4,5-dihydroxybenzaldehyde
• CIS-ENTACAPONE
• (E)-3-O-Methyl Entacapone
• 3,5-DINITROCATECHOL
• 3,4-Dihydroxy-5-Nitrobenzoic Acid
• (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
• (alphaE)-alpha-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-beta-oxo-1-piperidinepropanenitrile
• Entacapone EP Impurity G
• Entacapone EP IMpurity B
• Entacapone Impurity 10
• Entacapone Impurity 4
• 6-Methoxy-2,4-dinitrophenol
• Entacapone 3-b-D-Glucuronide
• Entacapone Impurity 13
• 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N,N-diethyl-, (2E)-
• Entacapone EP IMpurity D