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1-Cbz-4-Piperidone

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1-Cbz-4-Piperidone Basic information

Product Name:
1-Cbz-4-Piperidone
Synonyms:
  • 1-(BENZYLOXYCARBONYL)-4-PIPERIDINONE
  • 1-CARBOBENZOXY-4-PIPERIDONE
  • 1-N-CBZ-4-PIPERIDONE
  • 1-Z-4-PIPERIDONE
  • PIPERIDIN-4-ONE, CBZ PROTECTED
  • N-CBZ-4-PIPERIDONE
  • N-BENZYLOXYCARBONYLPIPERIDIN-4-ONE
  • N-BENZYLOXYCARBONYLPIPERIDONE
CAS:
19099-93-5
MF:
C13H15NO3
MW:
233.26
EINECS:
606-227-7
Product Categories:
  • Piperidine Series
  • Building Blocks
  • Piperidines
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Piperidones
  • Miscellaneous Biochemicals
  • Pyrans, Piperidines &Piperazines
  • API intermediates
  • Aromatics
  • Heterocycles
  • Pyrans, Piperidines & Piperazines
  • 19099-93-5
Mol File:
19099-93-5.mol
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1-Cbz-4-Piperidone Chemical Properties

Melting point:
38-41°C
Boiling point:
114-140 °C/0.25 mmHg (lit.)
Density 
1.172 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.542(lit.)
Flash point:
>110 °C
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform, Dichloromethane, Ethyl Acetate, Methanol
pka
-1.63±0.20(Predicted)
form 
Solid or Lliquid
Specific Gravity
1.185
color 
White to pale yellow
BRN 
1533716
InChI
InChI=1S/C13H15NO3/c15-12-6-8-14(9-7-12)13(16)17-10-11-4-2-1-3-5-11/h1-5H,6-10H2
InChIKey
VZOVOHRDLOYBJX-UHFFFAOYSA-N
SMILES
N1(C(OCC2=CC=CC=C2)=O)CCC(=O)CC1
CAS DataBase Reference
19099-93-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-24/25-36-26-37/39
WGK Germany 
3
HS Code 
29333990

MSDS

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1-Cbz-4-Piperidone Usage And Synthesis

Chemical Properties

Colourless Oil

Uses

Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.3

General Description

1-Cbz-4-Piperidone is the starting material in biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol condensation reactions.

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