1-Cbz-4-Piperidone Chemical Properties

Melting point:

38-41°C

Boiling point:

114-140 °C/0.25 mmHg (lit.)

Density 

1.172 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.542(lit.)

Flash point:

>110 °C

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform, Dichloromethane, Ethyl Acetate, Methanol

pka

-1.63±0.20(Predicted)

form 

Solid or Lliquid

Specific Gravity

1.185

color 

White to pale yellow

BRN 

1533716

InChI

InChI=1S/C13H15NO3/c15-12-6-8-14(9-7-12)13(16)17-10-11-4-2-1-3-5-11/h1-5H,6-10H2

InChIKey

VZOVOHRDLOYBJX-UHFFFAOYSA-N

SMILES

N1(C(OCC2=CC=CC=C2)=O)CCC(=O)CC1

CAS DataBase Reference

19099-93-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

23-24/25-36-26-37/39

WGK Germany 

3

HS Code 

29333990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1-Cbz-4-Piperidone Usage And Synthesis

Chemical Properties

Colourless Oil

Uses

Protected piperidinone that can undergo interesting synthetic transformations including the Knoevenagel reaction,1 hetero-Diels-Alder reactions,2 and reactions to form N-(4-piperidinyl)oxindoles.3

General Description

1-Cbz-4-Piperidone is the starting material in biheteroaromatic diphosphine oxides-catalyzed stereoselective direct aldol condensation reactions.

1-Cbz-4-Piperidone(19099-93-5)Related Product Information

• 2-Piperidone
• N-Carbethoxy-4-piperidone
• 4,4-Piperidinediol hydrochloride
• tert-Butyl carbazate
• Thalidomide
• DROPERIDOL
• Benzyl alcohol
• Haloperidol
• Benzyl bromide
• Trimethoprim
• N-Carbobenzyloxyglycine
• 4-Piperidinone
• Benzyl benzoate
• 1-BENZYL 4-ETHYL PIPERIDINE-1,4-DICARBOXYLATE
• 4-CARBOXYMETHOXY-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
• 1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid
• Diphenoxylate
• 1-CBZ-2-PHENYL-PIPERIDIN-4-ONE