H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Chemical Properties

Boiling point:

2391.5±65.0 °C(Predicted)

Density 

1.319±0.06 g/cm3(Predicted)

storage temp. 

-20°C

form 

Solid

Water Solubility 

Soluble to 1 mg/ml in water

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH Usage And Synthesis

Uses

[Ala^1,3,11,15]-Endothelin 1 may be used to assess the effects of endothelin-1 and [Ala^1,3,11,15]-endothelin 1 produced by ETA and ETB receptors, in the presence of BQ-123, in anaesthetized rat.

General Description

[Ala^1,3,11,15]-Endothelin 1 is a linear endothelin (ET)-1 analogue, and acts as an ETB receptor agonist. ET-1 is a peptide that acts as both, a vasodilator and a vasoconstrictor. It is a ligand for ET receptor, which is of two types, ETA and ETB. ETB receptor is found in the vascular endothelial cells of cardiovascular tissues.

Biochem/physiol Actions

Selective agonist for ETB endothelin receptors.

H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH(121204-87-3)Related Product Information

• AC-GLY-TRP-OH
• H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
• Endothelin-1 (human, porcine)
• ENDOTHELIN-1 [ALA1,3,11,15] [3-(125I)TYR] (HUMAN)
• BQ-3020
• H-ILE-TRP-OH
• ENDOTHELIN (16-21)
• ([125I]-TYR)-ENDOTHELIN-1 (HUMAN, BOVINE, DOG, MOUSE, PORCINE, RAT)
• H-VAL-TRP-OH
• H-GLY-GLY-TRP-OH