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DEOXYSHIKONIN

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DEOXYSHIKONIN Basic information

Product Name:
DEOXYSHIKONIN
Synonyms:
  • 5,8-DIHYDROXY-2-(4-METHYL-3-PENTENYL)-1,4-NAPHTHALENEDIONE
  • DEOXYSHIKONIN
  • Arnebin VII
  • Deoxyalkannin
  • Anhydroalkanin
  • Arnebin 7
  • NSC 179184
  • 5,8-dihydroxy-2-(4-methylpent-3-enyl)naphthalene-1,4-dione
CAS:
43043-74-9
MF:
C16H16O4
MW:
272.3
Mol File:
43043-74-9.mol
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DEOXYSHIKONIN Chemical Properties

Melting point:
91°C
Boiling point:
503.7±50.0 °C(Predicted)
Density 
1.269±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
7.42±0.20(Predicted)
color 
Brown to reddish brown
CAS DataBase Reference
43043-74-9
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Safety Information

Safety Statements 
22-24/25
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DEOXYSHIKONIN Usage And Synthesis

Uses

Deoxyshikonincan be used as a natural pigment in cosmetics and printing and dyeing industries, and has great development and application prospects.

Definition

ChEBI: Deoxyshikonin is a hydroxy-1,4-naphthoquinone.

in vivo

Deoxyshikonin (20?mg/kg; intraperitoneal injection; every two days for 13 days) markedly suppresses the growth of xenograft tumours on day 5, 9 and 11 with 20?mg/kg[1].

Animal Model:Male BALB/c nude mice of 10-14?g with DLD-1 cells[1]
Dosage:20?mg/kg
Administration:Intraperitoneal injection; every two days for a total of 13 days
Result:Markedly suppressed the growth of xenograft tumours on day 5, 9 and 11 with 20?mg/kg, while there were no significant changes in body weight of the mice.

IC 50

HIF-1α; HIF-1β; PI3K

DEOXYSHIKONINSupplier

J & K SCIENTIFIC LTD.
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Energy Chemical
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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chenyj@titansci.com
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DEOXYSHIKONIN(43043-74-9)Related Product Information