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2-Hydroxy-4-methylpyridine

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2-Hydroxy-4-methylpyridine Basic information

Product Name:
2-Hydroxy-4-methylpyridine
Synonyms:
  • 2-HYDROXY-4-PICOLINE
  • 4-METHYL-2(1H)-PYRIDINONE
  • 4-METHYL-2(1H)-PYRIDONE
  • 4-METHYL-PYRIDIN-2-OL
  • 4-METHYL-2-PYRIDINOL
  • 4-METHYL-2-PYRIDONE
  • 2-HYDROXY-4-METHYLPYRIDINE 97%
  • 2-Hydroxy-4-Piocoline
CAS:
13466-41-6
MF:
C6H7NO
MW:
109.13
EINECS:
627-289-1
Product Categories:
  • Heterocycle-Pyridine series
  • Pyridines
  • Pyridine
  • Pyridine Series
  • pharmacetical
Mol File:
13466-41-6.mol
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2-Hydroxy-4-methylpyridine Chemical Properties

Melting point:
131-134 °C (lit.)
Boiling point:
186-187 °C/12 mmHg (lit.)
Density 
1.1143 (rough estimate)
refractive index 
1.5444 (estimate)
Flash point:
186-187°C/12mm
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
pK1:4.529(+1) (25°C)
color 
White to Gray to Brown
BRN 
107082
InChIKey
YBDRFJXGJQULGH-UHFFFAOYSA-N
CAS DataBase Reference
13466-41-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-37/39-36-22
WGK Germany 
3
HS Code 
29333995

MSDS

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2-Hydroxy-4-methylpyridine Usage And Synthesis

Chemical Properties

off-white to light brown crystalline powder

Uses

2-Hydroxy-4-methylpyridine is an intermediate used to prepare oxobenzopyrancarboxylate derivatives as inhibitors of serine proteases and human leukocyte elastase. It is also used in the synthesis of (indanylamino)(pyridinyloxy)pyrazines and analogs as corticotropin releasing factor type-1 receptor antagonists.

Definition

ChEBI: 2-Hydroxy-4-methylpyridine is a member of methylpyridines.

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