Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  Aliphatic aldehydes >  Methylglyoxal 1,1-dimethyl acetal

Methylglyoxal 1,1-dimethyl acetal

Basic information Safety Supplier Related

Methylglyoxal 1,1-dimethyl acetal Basic information

Product Name:
Methylglyoxal 1,1-dimethyl acetal
Synonyms:
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL
  • PYRUVALDEHYDE DIMETHYLACETAL
  • PYRUVALDEHYDE 1,1-DIMETHYL ACETAL
  • PYRUVALDEHYDE-1-DIMETHYL ACETAL
  • Methylglyoxal dimethyl acetal~Pyruvaldehyde dimethyl acetal
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL, 97+%
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL 98%
  • PYRUVIC ALDEHYDE DIMETHYL ACETAL(INTERMEDIATE OF B-CAROTENE)
CAS:
6342-56-9
MF:
C5H10O3
MW:
118.13
EINECS:
228-735-4
Product Categories:
  • ACETYLGROUP
  • Aldehydes
  • blocks
  • BuildingBlocks
  • ketone
  • (intermediate of -carotene)
Mol File:
6342-56-9.mol
More
Less

Methylglyoxal 1,1-dimethyl acetal Chemical Properties

Melting point:
-57 °C
Boiling point:
143-147 °C(lit.)
Density 
0.976 g/mL at 25 °C(lit.)
vapor pressure 
11hPa at 20℃
refractive index 
n20/D 1.398(lit.)
Flash point:
100 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Liquid
color 
Clear colorless to yellow
Water Solubility 
MISCIBLE
BRN 
1560557
InChIKey
ULVSHNOGEVXRDR-UHFFFAOYSA-N
LogP
-0.199 (est)
CAS DataBase Reference
6342-56-9
NIST Chemistry Reference
2-Propanone, 1,1-dimethoxy-(6342-56-9)
EPA Substance Registry System
2-Propanone, 1,1-dimethoxy- (6342-56-9)
More
Less

Safety Information

Hazard Codes 
Xi
Risk Statements 
10-36/38
Safety Statements 
26-36-16
RIDADR 
UN 1224 3/PG 3
WGK Germany 
1
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29145000

MSDS

More
Less

Methylglyoxal 1,1-dimethyl acetal Usage And Synthesis

Chemical Properties

clear colorless to yellow liquid

Uses

Pyruvic Aldehyde Dimethyl Acetal is used in the preparation of MCL1 inhibitors S63845 which is tolerable and effective in diverse cancer models. Also, acts as a synthetic reagent for the preparation of 8novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase. Selective inhibition of neuronal nitric oxide synthase is an important therapeutic approach to target neurodegenerative disorders.

Uses

Methylglyoxal 1,1-dimethyl acetal was used in the synthesis of methylglyoxal via hydrolysis in the presence of H2SO4. It was used to investigate the effects of methylglyoxal-mediated glycation on the structure, thermal stability and enzyme activity of yeast enolase in vivo.

Synthesis Reference(s)

The Journal of Organic Chemistry, 41, p. 2642, 1976 DOI: 10.1021/jo00877a030

Methylglyoxal 1,1-dimethyl acetal Preparation Products And Raw materials

Preparation Products

Raw materials

Methylglyoxal 1,1-dimethyl acetalSupplier

Shenyang NovPharm Technology Co., Ltd. Gold
Tel
024-24165786 18624046968
Email
novpharm@hotmail.com
Jinan Yuanze Biotechnology Co., LTD Gold
Tel
15063396929; 15063396929
Email
978101703@qq.com
Huai Hua Binfengchem Co., Ltd Gold
Tel
0745-2866851 17307457092
Email
sales@bingfengchem.com
Shandong Yinsheng Pharmaceutical Technology Co., Ltd Gold
Tel
1885-4110848 18865947357
Email
liguiling16888@163.com
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83946278 13820503911
Email
sales@creasyn.com