Methylglyoxal 1,1-dimethyl acetal
Methylglyoxal 1,1-dimethyl acetal Basic information
- Product Name:
- Methylglyoxal 1,1-dimethyl acetal
- Synonyms:
-
- PYRUVIC ALDEHYDE DIMETHYL ACETAL
- PYRUVALDEHYDE DIMETHYLACETAL
- PYRUVALDEHYDE 1,1-DIMETHYL ACETAL
- PYRUVALDEHYDE-1-DIMETHYL ACETAL
- Methylglyoxal dimethyl acetal~Pyruvaldehyde dimethyl acetal
- PYRUVIC ALDEHYDE DIMETHYL ACETAL, 97+%
- PYRUVIC ALDEHYDE DIMETHYL ACETAL 98%
- PYRUVIC ALDEHYDE DIMETHYL ACETAL(INTERMEDIATE OF B-CAROTENE)
- CAS:
- 6342-56-9
- MF:
- C5H10O3
- MW:
- 118.13
- EINECS:
- 228-735-4
- Product Categories:
-
- ACETYLGROUP
- Aldehydes
- blocks
- BuildingBlocks
- ketone
- (intermediate of -carotene)
- Mol File:
- 6342-56-9.mol
Methylglyoxal 1,1-dimethyl acetal Chemical Properties
- Melting point:
- -57 °C
- Boiling point:
- 143-147 °C(lit.)
- Density
- 0.976 g/mL at 25 °C(lit.)
- vapor pressure
- 11hPa at 20℃
- refractive index
- n20/D 1.398(lit.)
- Flash point:
- 100 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Liquid
- color
- Clear colorless to yellow
- Water Solubility
- MISCIBLE
- BRN
- 1560557
- InChIKey
- ULVSHNOGEVXRDR-UHFFFAOYSA-N
- LogP
- -0.199 (est)
- CAS DataBase Reference
- 6342-56-9
- NIST Chemistry Reference
- 2-Propanone, 1,1-dimethoxy-(6342-56-9)
- EPA Substance Registry System
- 2-Propanone, 1,1-dimethoxy- (6342-56-9)
MSDS
- Language:English Provider:1,1-Dimethoxyacetone
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
Methylglyoxal 1,1-dimethyl acetal Usage And Synthesis
Chemical Properties
clear colorless to yellow liquid
Uses
Pyruvic Aldehyde Dimethyl Acetal is used in the preparation of MCL1 inhibitors S63845 which is tolerable and effective in diverse cancer models. Also, acts as a synthetic reagent for the preparation of 8novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase. Selective inhibition of neuronal nitric oxide synthase is an important therapeutic approach to target neurodegenerative disorders.
Uses
Methylglyoxal 1,1-dimethyl acetal was used in the synthesis of methylglyoxal via hydrolysis in the presence of H2SO4. It was used to investigate the effects of methylglyoxal-mediated glycation on the structure, thermal stability and enzyme activity of yeast enolase in vivo.
Synthesis Reference(s)
The Journal of Organic Chemistry, 41, p. 2642, 1976 DOI: 10.1021/jo00877a030
Methylglyoxal 1,1-dimethyl acetal Preparation Products And Raw materials
Preparation Products
Raw materials
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Methylglyoxal 1,1-dimethyl acetal(6342-56-9)Related Product Information
- Chloroacetaldehyde dimethyl acetal
- Paraldehyde
- Acetal
- 1,1-Dimethoxyethane
- Benzaldehyde dimethyl acetal
- 1-Nonanal
- Diphenyldimethoxysilane
- Dimethyldimethoxysilane
- Methylglyoxal
- Acetylacetaldehyde dimethyl acetal
- Bromoacetaldehyde dimethyl acetal
- Methoxyacetone
- 4-Methoxyphenylacetone
- Benzhydrol
- 2,2-Dimethoxypropane
- 1,1,2-Trimethoxyethane
- N,N-Dimethylformamide
- Dimethyl fumarate
- Methylglyoxal Dimethyl Acetal