Anethole trithione
Anethole trithione Basic information
- Product Name:
- Anethole trithione
- Synonyms:
-
- Anetholi Trithionum
- 5-(4-methoxyphenyl)dithiole-3-thione
- (E)-O-4-(prop-1-enyl)-5,6-dithioxocyclohexa-1,3-dienyl methanethioate
- 4-(prop-1-en-1-yl)-5,6-disulfanylidenecyclohexa-1,3-dien-1-yl carbothioate
- Anethol trithione ,5-(4-Methoxyphenyl)-1,2-dithiole-3-thione
- Anethali Trithinum
- ANETHOLE TRITHIONE
- 5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione
- CAS:
- 532-11-6
- MF:
- C10H8OS3
- MW:
- 240.36
- EINECS:
- 208-528-5
- Mol File:
- 532-11-6.mol
Anethole trithione Chemical Properties
- Melting point:
- 111°
- Boiling point:
- 353.09°C (rough estimate)
- Density
- 1.4406 (rough estimate)
- refractive index
- 1.5080 (estimate)
- storage temp.
- 2-8°C
- solubility
- soluble in Chloroform
- form
- powder to crystal
- color
- Orange-colored prisms from butyl acetate
- Odor
- very bitter taste
- CAS DataBase Reference
- 532-11-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6)
Anethole trithione Usage And Synthesis
Description
Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.
Originator
Sialor,Paladin Labs
Uses
choleretic
Definition
ChEBI: Anetholtrithion is a member of methoxybenzenes.
Manufacturing Process
1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.
Therapeutic Function
Salivation stimulant, Choleretic, Neuroprotective
Safety Profile
Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.
Anethole trithione Preparation Products And Raw materials
Raw materials
Anethole trithioneSupplier
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Anethole trithione(532-11-6)Related Product Information
- 1,3-Cyclopentadiene
- 1,2-PENTADIENE
- 4-Methoxyphenylacetone
- TRANS-1,3-PENTADIENE
- DL-Limonene
- Cyclopentene
- Dicyclopentadiene
- trans-Anethole
- METHYLCYCLOPENTADIENE DIMER
- N,N-DIETHYLNICOTINAMIDE
- GALL
- Chicken gold
- BENZYL METHYL DISULFIDE
- cis-Anethol
- 5-PHENYL-3H-1,2-DITHIOLE-3-THIONE
- 3H-1,2-DITHIOLE-3-THIONE
- Anethole trithione