Basic information Description Safety Supplier Related
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Anethole trithione

Basic information Description Safety Supplier Related

Anethole trithione Basic information

Product Name:
Anethole trithione
Synonyms:
  • Anetholi Trithionum
  • 5-(4-methoxyphenyl)dithiole-3-thione
  • (E)-O-4-(prop-1-enyl)-5,6-dithioxocyclohexa-1,3-dienyl methanethioate
  • 4-(prop-1-en-1-yl)-5,6-disulfanylidenecyclohexa-1,3-dien-1-yl carbothioate
  • Anethol trithione ,5-(4-Methoxyphenyl)-1,2-dithiole-3-thione
  • Anethali Trithinum
  • ANETHOLE TRITHIONE
  • 5-(4-methoxyphenyl)-3h-1,2-dithiole-3-thione
CAS:
532-11-6
MF:
C10H8OS3
MW:
240.36
EINECS:
208-528-5
Mol File:
532-11-6.mol
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Anethole trithione Chemical Properties

Melting point:
111°
Boiling point:
353.09°C (rough estimate)
Density 
1.4406 (rough estimate)
refractive index 
1.5080 (estimate)
storage temp. 
2-8°C
solubility 
soluble in Chloroform
form 
powder to crystal
color 
Orange-colored prisms from butyl acetate
Odor
very bitter taste
CAS DataBase Reference
532-11-6(CAS DataBase Reference)
NIST Chemistry Reference
3H-1,2-Dithiole-3-thione, 5-(4-methoxyphenyl)-(532-11-6)
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Safety Information

HS Code 
2934.99.3000
Toxicity
LD50 orl-mus: 3850 mg/kg NIIRDN 6,25,82
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Anethole trithione Usage And Synthesis

Description

Anise trisulfide, also known as bile vita, is a secretory choleretic drug, which can significantly enhance liver glutathione levels, significantly enhance glutamyl cysteine synthase, glutathione reductase and glutathione sulfur Transferase activity, reduce glutathione peroxidase activity, enhance liver cell viability, and increase bile secretion. Without increasing the burden on the liver, it can reduce liver portal pressure, eliminate liver congestion and other symptoms of hepatitis lesions, promote liver cell activation, and contribute to the improvement and recovery of liver function.

Originator

Sialor,Paladin Labs

Uses

choleretic

Definition

ChEBI: Anetholtrithion is a member of methoxybenzenes.

Manufacturing Process

1 mol anethol (1-methoxy-4-propenyl-benzene) and 3 mol sulfur were heated in an open vessel to temperature 190°-200°C. H2S was removed at this temperature. On cooling the reaction mixture was getting solid. The solid product was recrystallizated from acetone or ethanol to give the orange-red needles of 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione; MP 108.5°C.

Therapeutic Function

Salivation stimulant, Choleretic, Neuroprotective

Safety Profile

Poison by intramuscular route.Moderately toxic by ingestion and intraperitoneal routes.Experimental reproductive effects. When heated todecomposition it emits toxic fumes of SOx.

Anethole trithione Preparation Products And Raw materials

Raw materials

Anethole trithioneSupplier

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