Basic information Safety Supplier Related

I-PROPYLISOCYANIDE

Basic information Safety Supplier Related

I-PROPYLISOCYANIDE Basic information

Product Name:
I-PROPYLISOCYANIDE
Synonyms:
  • ISOPROPYLISOCYANIDE
  • I-PROPYLISOCYANIDE
  • 2-isocyanopropane
  • 2-Isocyano-propane
  • 2-Isonitrilopropane
  • Isopropyl-isonitrile
  • 1-Propylisocyanide
  • i-Propylisocyanide,99%
CAS:
598-45-8
MF:
C4H7N
MW:
69.11
Product Categories:
  • organic compound
  • Isocyanides
  • Nitrogen Compounds
  • Organic Building Blocks
Mol File:
598-45-8.mol
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I-PROPYLISOCYANIDE Chemical Properties

Boiling point:
75 °C(lit.)
Density 
0.733 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.371(lit.)
Flash point:
69 °F
storage temp. 
2-8°C
form 
liquid
Specific Gravity
0.7596
color 
colorless
Stability:
store cold
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25
Safety Statements 
16-23-26-33-36/37/39-45
RIDADR 
UN 1992 3/PG 2
WGK Germany 
3

MSDS

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I-PROPYLISOCYANIDE Usage And Synthesis

Uses

Isopropyl isocyanide may be used in the preparation of:

  • Ugi ligand A2C11I1, which is employed in the solid-phase Ugi synthesis.
  • Pentafluorophenyl (PFP) functional monomers, via Passerini reaction.
  • Dinuclear copper complex [Cu2(μ-PiPr2bipy)2{μ-CNCH(CH3)2}](PF6)2 [PiPr2bipy = 6-(diisopropylphosphanyl)-2,2′-bipyridine].
  • (3E)-(Imino)thiaisoindoline 1,1-dioxide derivative.
  • N,N′-diisopropylcarbodiimide (DIC) analog via reaction with propan-2-amine.
  • 1-t-butyl-2-isopropyldiaziridinone via reaction with 2-methyl-2-nitrosopropane
  • isopropyl isocyanate via reaction with ozone
  • 1-phthalimidoazetidines via [1+3]cycloaddition reaction with 1-pththalimidoaziridines

Preparation

To a flask containing 100 ml (0.85 mole) of distilled quinoline is added with stirring 41 gm (0.214 mole) of /7-toluenesulfonyl chloride (see Note), and the solution is warmed to 75°C. Then 18.4 gm (0.212 mole) of isopropylformamide is added and the pressure of the system is reduced to 70 mm Hg. The isopropylisonitrile as it forms distills into a liquid nitrogencooled receiver. (Dry ice is not as effective but may be used.) The product is redistilled to afford 4.2 gm (30%), b.p. 88-89°C (735 mm Hg).

General Description

Isopropyl isocyanide is an alkyl isocyanide.

I-PROPYLISOCYANIDESupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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Energy Chemical
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021-021-58432009 400-005-6266
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sales8178@energy-chemical.com
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653715
Email
xingui2022@126.com
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I-PROPYLISOCYANIDE(598-45-8)Related Product Information