6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID Chemical Properties

Melting point:

187-189 °C(lit.)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Dark Beige

CAS DataBase Reference

56305-04-5

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

2

RTECS 

DJ2273000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID Usage And Synthesis

Uses

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid is a freeradical inhibitor, this is a water soluble derivative of vitamin e. Studies indicate it penetrates the skin more effectively than vitamin e, and that as an anti-oxidant it is more effective than BHT. It can be used in moisturizing lotions.

Definition

ChEBI: Trolox is a chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures. It has a role as an antioxidant, a radical scavenger, a Wnt signalling inhibitor, a neuroprotective agent and a ferroptosis inhibitor. It is a chromanol, a member of phenols and a monocarboxylic acid.

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