2-Amino-5-bromonicotinic acid Chemical Properties

Melting point:

253-255°C

Boiling point:

350.4±42.0 °C(Predicted)

Density 

1.909

refractive index 

1.5150 (estimate)

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

form 

powder

pka

2.55±0.10(Predicted)

color 

Pale yellow

CAS DataBase Reference

52833-94-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26

RIDADR 

UN2811

HazardClass 

IRRITANT

HS Code 

29333990

MSDS

• Language:English Provider:ACROS

2-Amino-5-bromonicotinic acid Usage And Synthesis

Uses

2-Amino-5-bromonicotinic acid is an organic intermediate that can be prepared by brominating 2-aminonicotinic acid. Literature reports that 2-amino-5-bromonicotinic acid can be used to prepare 6-pyrazole-substituted quinazoline compounds and their derivatives. These compounds exhibit high tyrosine kinase inhibitory activity and strong inhibitory activity against human breast cancer cells and lung adenocarcinoma cells.

Chemical Properties

Light yellow powder

References

[1] Patent: US6369056, 2002, B1
[2] Patent: US6399593, 2002, B1
[3] Patent: US2006/30583, 2006, A1. Location in patent: Page/Page column 113
[4] Patent: CN106565684, 2017, A. Location in patent: Paragraph 0177; 0178; 0179; 0180
[5] Patent: WO2014/209727, 2014, A1. Location in patent: Page/Page column 60-61

2-Amino-5-bromonicotinic acid(52833-94-0)Related Product Information

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