ChemicalBook > Product Catalog > Biochemical Engineering > Plant extracts > Plant Extracts > Catalpol
Catalpol
Catalpol Basic information
- Product Name:
- Catalpol
- Synonyms:
-
- Catalponol
- 1(2H)-Naphthalenone,3,4-dihydro-4-hydroxy- 2-(3-methyl-2-butenyl)-,(2R,4S)-
- 1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-buten-1-yl)-, (2R,4S)-
- Catalpol USP/EP/BP
- CAS:
- 34168-56-4
- MF:
- C15H18O2
- MW:
- 230.3
- Mol File:
- 34168-56-4.mol
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Catalpol Chemical Properties
- Boiling point:
- 369.8±31.0 °C(Predicted)
- Density
- 1.095±0.06 g/cm3(Predicted)
- pka
- 13.79±0.40(Predicted)
- CAS DataBase Reference
- 34168-56-4
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Catalpol Usage And Synthesis
Uses
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2].
References
[1] Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. DOI:10.1080/10286020903193094
[2] Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. DOI:10.1007/s12272-010-0306-2
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