ANDROGRAPHOLIDE, DEOXY-
ANDROGRAPHOLIDE, DEOXY- Basic information
- Product Name:
- ANDROGRAPHOLIDE, DEOXY-
- Synonyms:
-
- ANDROGRAPHOLIDE, DEOXY-
- DEOXYANDROGRAPHOLIDE
- 4-[2-[(4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalen-1-yl]ethyl]-2H-furan-5-one
- 2(5H)-Furanone, 3-[2-[(4aS,5R,6R,8aR)-3,4,4a,5,6,7,8,8a-octahydro-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-1-naphthalenyl]ethyl]-
- 3-[2-[(4aS,5R,6R,8aR)-3,4,4a,5,6,7,8,8a-Octahydro-6-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-1-naphthalenyl]ethyl]-2(5H)-furanone
- 3-(2-((4aS,5R,6R,8aR)-6-Hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)ethyl)furan-2(5H)-one
- CAS:
- 79233-15-1
- MF:
- C20H30O4
- MW:
- 334.45
- EINECS:
- 2017-001-1
- Mol File:
- 79233-15-1.mol
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ANDROGRAPHOLIDE, DEOXY- Chemical Properties
- Boiling point:
- 511.7±50.0 °C(Predicted)
- Density
- 1.123±0.06 g/cm3(Predicted)
- pka
- 14.89±0.70(Predicted)
- CAS DataBase Reference
- 79233-15-1
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ANDROGRAPHOLIDE, DEOXY- Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Andrographis paniculata (Burm. f.) Nees.
Uses
Deoxyandrographolide has antipyretic, anti-inflammatory, anti-leptin properties. Treponema pallidosis, antibacterial, anticancer, hepatoprotective and antihypertensive activities.
Biological Activity
Deoxyandrographolide, isolated from Andrographis paniculata, inhibits LPS-induced elevation of iNOS mRNA levels and production of pro-inflammatory mediators TNF-α and IL-6. It enhances NGF-induced neurite outgrowth.
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- ANDROGRAPHOLIDE, DEOXY-
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- ANDROGRAPHOLIDE, DEOXY(SH)