Bromo-PEG4-t-butyl ester Chemical Properties

Boiling point:

415.8±35.0 °C(Predicted)

Density 

1.210±0.06 g/cm3(Predicted)

solubility 

Soluble in DMSO, DCM, DMF

Bromo-PEG4-t-butyl ester Usage And Synthesis

Description

Bromo-PEG4-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Biological Activity

Br-PEG4-C2-Boc is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

target

Bromo-PEG4-t-butyl ester(564476-32-0)Related Product Information

• Tetraethyl decamethylenediphosphonate, 98%
• Bromo-PEG3-Acid
• Ethanol, 2-(2-bromoethoxy)-
• Bromo-PEG1-CH2CO2tBu
• Amino-PEG5-t-butyl ester
• H2N-PEG2-tBu
• H2N-PEG4-tBu
• Bromoacetic acid
• Methyl bromoacetate
• tert-Butyl acetate
• tert-Butyl 2-bromo-2-methylpropanoate
• Phosphorus tribromide
• Br-PEG5-acid
• Bromo-PEG3-t-butyl ester
• Bromo-PEG5-t-butyl ester
• Bromo-PEG6-t-butyl ester
• Bromo-PEG4-acid
• Bromo-PEG2-acid