N-Acetyl-DL-phenylalanine Chemical Properties

Melting point:

152.0 to 156.0 °C

Boiling point:

453.9±38.0 °C(Predicted)

Density 

1.199±0.06 g/cm3(Predicted)

RTECS 

SQ7321132

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

pka

3.56±0.10(Predicted)

form 

Powder

color 

Off-white

λmax

280nm(lit.)

CAS DataBase Reference

2901-75-9(CAS DataBase Reference)

Safety Information

WGK Germany 

3

HS Code 

2924.29.7790

MSDS

• Language:English Provider:SigmaAldrich

N-Acetyl-DL-phenylalanine Usage And Synthesis

Originator

Afalanine ,Sankyo

Uses

N-Acetyl-DL-phenylalanine is an antidepressant, used to prevent kidney damage.

Definition

ChEBI: The N-acetyl derivative of phenylalanine.

Manufacturing Process

The phenylalanine was dispersed in water. A 1 N aqueous solution of sodium hydroxide was slowly added to this dispersion, and the pH of the solution reached a value of 7-8.
Then acetylbromide was dissolved in this solution, to give a Nacetylphenylalanine.

Therapeutic Function

Antidepressant

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 243, 1990 DOI: 10.1016/S0040-4039(00)94382-X

N-Acetyl-DL-phenylalanine(2901-75-9)Related Product Information

• DL-Malic acid
• D-Phenylalanine
• Ethyl 2-(Chlorosulfonyl)acetate
• DL-Phenylalanine
• Phenprobamate
• Acetyl chloride
• L-Phenylalanine
• Acetylacetone
• N-Acetyl-L-phenylalanine
• trans-Cinnamic acid
• L-Alanine
• 3-Phenylpropionic acid
• N-ALPHA-ACETYL-DL-PHENYLALANINE,ACETYL-DL-PHENYLALANINE,AC-DL-PHE-OH
• Cinnamic acid
• AC-DL-PHE-PNA
• N-Acetyl-DL-phenylalanine 4-nitrophenyl ester,ACETYL-DL-PHENYLALANINE 4-NITROPHENYL ESTER,N-ACETYL-DL-PHENYLALANINE P-NITROPHENYL ESTER
• AC-DL-PHE-BETA-NAPHTHYL ESTER
• N-Acetyl-DL-phenylalanine