3-Pyridineethaneamine Chemical Properties

Boiling point:

119-120°C 19mm

Density 

1.04

refractive index 

1.5518

Flash point:

119-120°C/19mm

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

clear liquid

pka

9.29±0.10(Predicted)

color 

Colorless to Almost colorless

Specific Gravity

1.04

Water Solubility 

Slightly soluble in water.

Sensitive 

Air Sensitive

BRN 

111288

CAS DataBase Reference

20173-24-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

34-41-37/38

Safety Statements 

26-36/37/39-39

RIDADR 

2735

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29333990

MSDS

• Language:English Provider:2-(3-Pyridyl)ethylamine
• Language:English Provider:ALFA

3-Pyridineethaneamine Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

3-(2-Aminoethyl)pyridine has been used in the synthesis of urea.

Synthesis

The general procedure for the synthesis of 3-(2-aminoethyl)pyridine from 3-pyridylacetonitrile was as follows: 2-(pyridin-3-yl)acetonitrile (1 g, 8.47 mmol, 1.00 eq.), nickel ryenne (1 g, 17.24 mmol, 1.00 eq.) and ammonium hydroxide (3 mL) were dissolved in methanol (15 mL). The mixture was stirred and reacted overnight at room temperature and 1 atm hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration through a diatomaceous earth pad and washed several times with methanol. The filtrate and washings were combined and concentrated in vacuum to give 940 mg (45% yield) of 2-(pyridin-3-yl)ethylamine as a yellow oil.LC-MS analysis: (ES, m/z): 164 [M + CH3CN + H]+, 123 [M + H]+, 106.

References

[1] Patent: WO2013/155338, 2013, A2. Location in patent: Page/Page column 180
[2] Patent: US2015/329503, 2015, A1. Location in patent: Paragraph 0720; 0721
[3] Patent: US6017919, 2000, A
[4] Journal of the American Chemical Society, 1980, vol. 102, # 17, p. 5530 - 5538
[5] Journal of the American Chemical Society, 1955, vol. 77, p. 6554,6556

3-Pyridineethaneamine(20173-24-4)Related Product Information

• 4-Dimethylaminopyridine
• 3-Hydroxypyridine
• Ethylamine
• Pyridine
• 2-(2-Aminoethylamino)ethanol
• 2-Chloro-3-hydroxypyridine
• 3-Aminopyridine
• 2-Aminopyridine
• 6-ANILINO-5,8-QUINOLINEDIONE
• dimebolin
• Boc-3-(3-pyridyl)-L-alanine
• L-3-Pyridylalanine
• ISONICOTINE
• (S)-N-Fmoc-(3-Pyridyl)alanine
• (R)-N-Boc-(3-Pyridyl)alanine
• 3-(3-Pyridyl)-D-alanine
• (R)-N-Fmoc-(3-Pyridyl)alanine
• (+)-EPIBATIDINE