4-Isopropylphenol Chemical Properties

Melting point:

59-61 °C (lit.)

Boiling point:

212-213 °C (lit.)

Density 

0.9900

vapor density 

>1 (vs air)

refractive index 

1.5228

Flash point:

108°C

storage temp. 

Store at +2°C to +8°C.

solubility 

Chloroform, Ethyl Acetate (Slightly), Methanol (Slightly)

pka

10.19±0.13(Predicted)

form 

Crystalline Mass or Crystals

color 

White to beige-brown

Odor

at 1.00 % in dipropylene glycol. woody warm spicy medicinal

Odor Type

woody

Water Solubility 

Slightly soluble in water, soluble in ethanol and ethyl ether.

BRN 

1363564

LogP

2.900

CAS DataBase Reference

99-89-8(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 4-(1-methylethyl)-(99-89-8)

EPA Substance Registry System

p-Isopropylphenol (99-89-8)

Safety Information

Hazard Codes 

C

Risk Statements 

22-34-43-52/53

Safety Statements 

26-36/37/39-45-61

RIDADR 

UN 2430 8/PG 3

WGK Germany 

2

RTECS 

SL5950000

Hazard Note 

Corrosive/Harmful

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29071900

MSDS

• Language:English Provider:p-Cumenol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Isopropylphenol Usage And Synthesis

Chemical Properties

WHITE TO BEIGE CRYSTALLINE SOLID

Uses

4-Isopropylphenol was used in the synthesis of vinyl compounds. It is used as a flavor & fragrance agent in cosmetics.

Uses

4-Isopropylphenol is an Impurity of Propofol (P829750).

Production Methods

4-Isopropylphenol is produced:
1) by isolation from Eucalyptus polybractea oil.
2) from Magnesium para-iso-propylphenyl-bromide by air oxidation.

Definition

ChEBI: 4-isopropylphenol is a member of the class of phenols that is phenol which is carrying an isopropyl group at position 4. It has a role as a flavouring agent. It derives from a hydride of a cumene.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 3889, 1949 DOI: 10.1021/ja01180a005
Synthesis, p. 396, 1978 DOI: 10.1055/s-1978-24762

General Description

Sonochemical degradation of 4-Isopropylphenol has been studied.

4-Isopropylphenol(99-89-8)Related Product Information

• M-ISOPROPYLPHENOL,Isopropylphenol, meta,3-ISOPROPYLPHENOL,3-ISOPROPYLPHENOL 97+%,3-ISOPROPYLPHENOL 98%,3-ISOPROPYLPHENOL 98+%,META-ISOPROPYLPHENOL
• 2,4-DIISOPROPYLPHENOL
• Propofol
• Phenol
• 2-Isopropoxyphenol
• 4-Isopropylbenzoic acid
• Lithium diisopropylamide
• N,N-Diisopropylethylamine
• Cuminaldehyde
• Cumene
• Diisopropylamine
• Chloromethyl isopropyl carbonate
• 4-ISOPROPYLBENZENESULFONYL CHLORIDE
• 4'-Isopropylacetophenone
• 4-Isopropylaniline
• O-ISOPROPYLPHENOL,2-ISOPROPYLPHENOL 98+%,Isopropylphenol, ortho,2-ISOPROPYLPHENOL
• 3,6-Diisopropyl-1,2-benzenediol
• 2,6-Diisopropyl-1,4-benzoquinone