PC Biotin-PEG3-Alkyne Chemical Properties

Boiling point:

1023.8±65.0 °C(Predicted)

Density 

1.245±0.06 g/cm3(Predicted)

storage temp. 

-20°C

pka

10.58±0.46(Predicted)

InChI

InChI=1S/C35H52N6O12S/c1-4-11-38-35(45)53-24(2)25-21-28(48-3)29(22-27(25)41(46)47)52-14-7-10-32(43)37-13-16-50-18-20-51-19-17-49-15-12-36-31(42)9-6-5-8-30-33-26(23-54-30)39-34(44)40-33/h1,21-22,24,26,30,33H,5-20,23H2,2-3H3,(H,36,42)(H,37,43)(H,38,45)(H2,39,40,44)/t24?,26-,30-,33-/m0/s1

InChIKey

HRHZIAGPIYYJMG-MJUSKHNJSA-N

SMILES

C(OC(C1=CC(OC)=C(OCCCC(=O)NCCOCCOCCOCCNC(=O)CCCC[C@H]2[C@@]3([H])NC(=O)N[C@@]3([H])CS2)C=C1[N+]([O-])=O)C)(=O)NCC#C

PC Biotin-PEG3-Alkyne Usage And Synthesis

Description

PC Biotin-PEG3-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. PEG spacer provides better solubility to the labeled molecules in aqueous media. Captured biomolecules can be efficiently photoreleased using near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Uses

PC biotin-alkyne is an azide-reactive photoclevable biotin probe that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an alkyne group through a spacer arm containing a photocleavable moiety. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low-intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm²).

PC Biotin-PEG3-Alkyne(1869922-24-6)Related Product Information

• Dde Biotin-PEG4-DBCO
• Diazo Biotin-PEG3-Alkyne
• PC Biotin-PEG3-Azide
• Dde Biotin-PEG4-Picolyl Azide
• Dde Biotin-PEG4-Azide
• 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID
• Diazo Biotin-PEG3-Azide