15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties

Boiling point:

784.8±60.0 °C(Predicted)

Density 

1.211±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

Soluble in Water, DMSO, DMF

pka

4.28±0.10(Predicted)

form 

Solid

color 

White to off-white

Appearance

white to beige powder

Safety Information

HS Code 

29349990

15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Usage And Synthesis

Description

Biotin-PEG4-acid is a biotinylation reagent which can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.

Chemical Properties

White powder

Uses

Biotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

IC 50

PEGs

15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID(721431-18-1)Related Product Information

• 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester
• 2,5,8,11,14,17,20-Heptaoxadocosane-22-thiol
• alpha-Azido-omega-hydroxy octa(ethylene glycol)
• 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
• Biotin-PEG6-OH
• Nonaethylene glycol
• 2-[2-(2-methoxyethoxy)ethoxy]ethylamine
• 2,5,8,11,14-Pentaoxahexadecan-16-amine
• HO-PEG10-tBu
• 2,5,8,11,14,17,20-Heptaoxadocosan-22-amine
• MPEG6-CH2CH2COOH
• HEXAETHYLENE GLYCOL MONOMETHYL ETHER
• DODECAETHYLENE GLYCOL
• HS-PEG8-CH2CH2COOH
• 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol
• 2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
• Biotin-PEG4- Picolyl Azide
• Biotin-PEG4-Amide-C6-Azide