2-[2-(2-methoxyethoxy)ethoxy]ethylamine Chemical Properties

Boiling point:

106℃ (11 Torr)

Density 

0.978±0.06 g/cm3(Predicted)

refractive index 

1.4395 (589.3 nm 20℃)

storage temp. 

2-8°C

solubility 

Soluble in Water, DMSO, DCM, DMF

form 

Oil

pka

8.74±0.10(Predicted)

Safety Information

HS Code 

2922190090

2-[2-(2-methoxyethoxy)ethoxy]ethylamine Usage And Synthesis

Description

m-PEG3-amine is a PEG reagent containing an amino group (NH2). The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG3-amine whose chemical name 2-[2-(2-methoxyethoxy)ethoxy]ethylamine,it is a PROTAC bridge, belonging to the PEG class, which can be used to synthesize a series of PROTAC molecules, and can also be used for the synthesis of antibody drug conjugates (ADCs).

Synthesis

2-[2-(2-methoxyethoxy)ethoxy]ethylamine is an organic intermediate, which can be prepared from triethylene glycol monomethyl ether as raw material to prepare 2-(2-(2-methoxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate, and then Reaction with sodium azide,and then Reacts with sodium azide to finally yield 3,6,9-trioxa-1-aminodecane.

2-[2-(2-methoxyethoxy)ethoxy]ethylamine(74654-07-2)Related Product Information

• OCTAETHYLENE GLYCOL MONOMETHYL ETHER
• Methyl-PEG3-MS
• Methyl-PEG9-t-butyl ester
• 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane
• Nonaethylene glycol
• HEXAETHYLENE GLYCOL MONOMETHYL ETHER
• BIOTIN-XX-NHS
• H2N-PEG24-tBu
• 2,5,8,11,14,17,20-Heptaoxadocosane-22-thiol
• Boc-1-amino-3,6-dioxa-8-octanediamine
• 2-(2-Methoxyethoxy)ethanamine
• alpha, oMega-Dipropionic acid triethylene glycol
• HS-PEG8-CH2CH2COOH
• 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane-28-thiol
• DODECAETHYLENE GLYCOL
• alpha-aMine-oMega-propionic acid octaethylene glycol
• N3-PEG6-tBu
• Amino-PEG2-acid