2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Chemical Properties

Boiling point:

437.2±40.0 °C(Predicted)

Density 

1.10

refractive index 

1.4950 to 1.4990

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in DMSO, DCM, DMF

form 

clear liquid

pka

14.36±0.10(Predicted)

color 

White to Yellow to Green

InChI

InChI=1S/C17H28O6/c18-6-7-19-8-9-20-10-11-21-12-13-22-14-15-23-16-17-4-2-1-3-5-17/h1-5,18H,6-16H2

InChIKey

UMUSOTNGYAALST-UHFFFAOYSA-N

SMILES

C(C1=CC=CC=C1)OCCOCCOCCOCCOCCO

Safety Information

HS Code 

2909498090

2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL Usage And Synthesis

Description

Benzyl-PEG6-alcohol is a PEG linker with a benzyl protecting group and a primary alcohol. The benzyl protecting group can be removed under acidic conditions. The primary alcohol can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

BnO-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC 50

PEGs

References

[1] Girardini M, et al. Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs. Bioorg Med Chem. 2019 Jun 15;27(12):2466-2479. DOI:10.1016/j.bmc.2019.02.048

2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL(57671-28-0)Related Product Information

• BnO-PEG5-CH2CH2NH2
• PENTAETHYLENE GLYCOL MONOMETHYL ETHER
• O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)NONAETHYLENE GLYCOL
• Benzyl-PEG6-azide
• Nonaethylene glycol Monobenzyl ether
• Benzyl-PEG6-THP
• Benzyl-PEG5-Azide
• Benzyl-PEG2-Azide
• 2-[2-(BENZYLOXY)ETHOXY]ETHANOL
• Benzyl-PEG7-amino
• Benzyl-PEG2-Amino
• Octaethylene glycol Monobenzyl ether
• 2-(Benzyloxyethoxyethoxy)ethylaMine
• Benzyl-PEG3-N3
• Benzyl-PEG6-Mes
• Benzyl-PEG7-alcohol
• 2-[2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
• Benzyl ether