alpha-Azido-omega-hydroxy octa(ethylene glycol) Chemical Properties

storage temp. 

2-8°C

solubility 

Soluble in Water, DMSO, DCM, DMF

form 

Liquid

color 

Colorless to light yellow

BRN 

8940056

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26

WGK Germany 

3

HS Code 

2929900090

alpha-Azido-omega-hydroxy octa(ethylene glycol) Usage And Synthesis

Description

Azide-PEG8-alcohol is a click chemistry reagent with an azide(N3) and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl (OH) group enables further derivatization or replacement with other functional groups.

Uses

O-(2-Azidoethyl)heptaethylene glycol is used to synthesize oligo and poly(ethylene glycol) derivatives that are used as structural units of dendrimers, hydrogels, surface modifiers, self-assembling systems and molecular crosslinkers. This precursor is compatible for acetylene-azide click reactions.

Some of the reported applications include:

• Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).
• Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.
• Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.
• Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).
• Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.
• Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.

alpha-Azido-omega-hydroxy octa(ethylene glycol)(352439-36-2)Related Product Information

• N3-PEG8-CH2CH2COOH
• Amino-PEG4-acid
• FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
• DODECAETHYLENE GLYCOL MONOMETHYL ETHER
• 2-[2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHOXY]ETHANOL
• HO-PEG8-CH2CH2COOH
• HO-PEG10-tBu
• O-(2-AMINOETHYL)-O-(2-AZIDOETHYL)HEPTAETHYLENE GLYCOL
• HS-PEG4-tBu
• α,ω-dipropionic acid tetraethylene glycol
• 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-amine
• alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol)
• N3-PEG3-tBu
• 2,5,8,11,14,17,20-Heptaoxadocosan-22-amine
• 3,6,9,12,15,18,21,24,27,30,33-Undecaoxatetratriacontan-1-amine
• 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL
• 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine
• 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid