Diazo Biotin-PEG3-Alkyne Chemical Properties

Boiling point:

1092.2±65.0 °C(Predicted)

Density 

1.31±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Soluble in DMSO

pka

8.48±0.45(Predicted)

Diazo Biotin-PEG3-Alkyne Usage And Synthesis

Description

Diazo Biotin-PEG3-alkyne is useful for introducing a biotin moiety to azide-containing biomolecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Diazo allows efficient release of captured biotinylated molecules from streptavidin using sodium dithionite (Na2S2O4).

Uses

Diazo biotin-alkyne is an alkyne-activated, sodium dithionite (Na₂S₂O₄) cleavable biotin probe that allows for efficient release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to an azide group through a spacer arm containing a diazo group that can be cleaved with 50 mM sodium dithionite solution.

Diazo Biotin-PEG3-Alkyne(1884349-58-9)Related Product Information

• Dde Biotin-PEG4-DBCO
• PC Biotin-PEG3-Azide
• Dde Biotin-PEG4-Picolyl Azide
• Dde Biotin-PEG4-Azide
• 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID
• PC Biotin-PEG3-Alkyne
• Diazo Biotin-PEG3-Azide