Fluorescein-DBCO CAS#: 2054339-00-1

Fluorescein-DBCO Basic information

Product Name:

Fluorescein-DBCO

Synonyms:

DBCO-FITC(5-isomer)
5-FITC-DBCO
Fluorescein-DBCO,FlITC-DBCO
Fluorescein-DBCO
Thiourea, N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-N'-(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)-
FITC-DBCO

CAS:

2054339-00-1

MF:

C39H27N3O6S

MW:

665.71

Mol File:

2054339-00-1.mol

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Fluorescein-DBCO Chemical Properties

Boiling point:: 969.9±75.0 °C(Predicted)
Density: 1.57±0.1 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light, stored under nitrogen
solubility: Soluble in DMSO, DMF, DCM
pka: 9.33±0.20(Predicted)
form: Solid
color: Yellow to orange

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Fluorescein-DBCO Usage And Synthesis

Description

Fluorescein-DBCO is a fluorescein dye labeling reagent containing a DBCO group, which can react with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst.

Biological Activity

Fluorescein-DBCO is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Non-cleavable

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Fluorescein-DBCOSupplier

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Shanghai Macklin Biochemical Co.,Ltd.

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