3,5-Dimethylphenol Chemical Properties

Melting point:

61-64 °C(lit.)

Boiling point:

222 °C(lit.)

Density 

1.115

refractive index 

1.5146 (estimate)

Flash point:

109 °C

storage temp. 

room temp

pka

pK1:10.15 (25°C)

form 

Crystalline Solid

color 

White to orange

Water Solubility 

5.3 g/L (25 ºC)

Sensitive 

Air & Light Sensitive

Merck 

14,10082

BRN 

774117

InChIKey

TUAMRELNJMMDMT-UHFFFAOYSA-N

CAS DataBase Reference

108-68-9(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 3,5-dimethyl-(108-68-9)

EPA Substance Registry System

3,5-Dimethylphenol (108-68-9)

Safety Information

Hazard Codes 

T

Risk Statements 

24/25-34

Safety Statements 

26-28-36/37/39-45-28A

RIDADR 

UN 2261 6.1/PG 2

WGK Germany 

2

RTECS 

ZE6475000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29071400

Hazardous Substances Data

108-68-9(Hazardous Substances Data)

MSDS

• Language:English Provider:3,5-Xylenol
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,5-Dimethylphenol Usage And Synthesis

Description

3,5-Dimethylphenol was used in simultaneous determination of urinary concentrations of phenol, o-, p-, m-cresols, 1-, 2-naphthol and xylenol isomers by capillary gas chromatography. It was used as starting reagent for total synthesis of landomycin A, most potent antitumor angucycline antibiotic and optically active polypropionate units. It also finds application as adhesives, sealant chemicals, plating and surface treating agents. It is also used as a solvent for cleaning or degreasing. Further, it is employed as a chemical intermediate for antioxidants, phenolic resins, active pharmaceutical ingredients and metaxalone (muscle relaxant).

Chemical Properties

WHITE TO LIGHT BEIGE CRYSTALLINE SOLID

Chemical Properties

3,5-Xylenol is a crystalline solid.

Definition

ChEBI: A member of the class of phenols that phenol substituted by methyl groups at positions 3 and 5.

General Description

Colorless to off-white crystalline solid. Odor threshold 1 ppm. Taste threshold 0.001 mg/L.

Air & Water Reactions

3,5-Dimethylphenol is hygroscopic. Insoluble in water.

Reactivity Profile

3,5-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides, and oxidizing agents. 3,5-Dimethylphenol corrodes steel, brass, copper, and copper alloys.

Fire Hazard

Flash point data for 3,5-Dimethylphenol are not available. 3,5-Dimethylphenol is probably combustible.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also other xylenol entries.

Potential Exposure

3,5-Xylenol is used as an antioxidant, solvent, plasticizer, wetting agent; and in pharmaceuticals. Xylenols are also used in pesticides, fuel, and lubricant additives; as a rubber chemical; in dyestuff manufacture. There are actually six xylenol isomers.

Shipping

UN 2261 Xylenols, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Purification Methods

Purify it as for 3,4-dimethylphenol. [Beilstein 6 IV 3141.]

Incompatibilities

A weak organic acid. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides.

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

3,5-Dimethylphenol(108-68-9)Related Product Information

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