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FERULIC ACID METHYL ESTER

Basic information Safety Supplier Related

FERULIC ACID METHYL ESTER Basic information

Product Name:
FERULIC ACID METHYL ESTER
Synonyms:
  • FERULIC ACID METHYL ESTER (METHYL FERULATE)
  • (SYNONYMS: METHYL FERULATE)
  • Methyl Ferulate [4-Hydroxy-3-MethoxycinnaMic Acid Methyl Ester]
  • METHYL 4-HYDROXY-3-METHOXYCINNAMATE
  • METHYL FERULATE
  • METHYL TRANS-3-(4'-HYDROXY-3'-METHOXYPHENYL)-ACRYLATE
  • METHYL 3-(4-HYDROXY-3-METHOXY)CINNAMATE
  • FERULIC ACID METHYL ESTER
CAS:
2309-07-1
MF:
C11H12O4
MW:
208.21
EINECS:
1308068-626-2
Product Categories:
  • Aromatic Esters
  • bc0001
Mol File:
2309-07-1.mol
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FERULIC ACID METHYL ESTER Chemical Properties

Melting point:
62-65°C
Boiling point:
163 °C(Press: 1 Torr)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Sparingly)
form 
Solid
pka
8.88±0.18(Predicted)
color 
White to Off-White
Water Solubility 
Slightly soluble in water.
LogP
2.209 (est)
CAS DataBase Reference
2309-07-1(CAS DataBase Reference)
NIST Chemistry Reference
2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, methyl ester(2309-07-1)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
RTECS 
GD9470000
HS Code 
2918999090

MSDS

  • Language:English Provider:ALFA
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FERULIC ACID METHYL ESTER Usage And Synthesis

Uses

Ferulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid methyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid methyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 74.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). Ferulic acid methyl ester, at 10-25 μg/ml, inhibits the release of pro-inflammatory cytokines, blocks the expression of COX-2, and reduces nitric oxide generation from LPS-stimulated macrophages.

Uses

Ferulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.

Definition

ChEBI: A cinnamate ester that is the methyl ester of ferulic acid. It has been isolated from Pisonia aculeata.

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