(D-TYR5)-GOSERELIN Chemical Properties

storage temp. 

-15°C

Sequence

{Pyr}-His-Trp-Ser-{d-Tyr}-{d-Ser(tBu)}-Leu-Arg-Pro-{Azagly}-NH2

InChIKey

BLCLNMBMMGCOAS-JRAHOCOPSA-N

(D-TYR5)-GOSERELIN Usage And Synthesis

Uses

(D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].

References

[1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499

(D-TYR5)-GOSERELIN(1426173-74-1)Related Product Information

• (Ser(tBu)6,Azagly10)-LHRH
• (D-SER6)-GOSERELIN
• (Glu1,D-Ser(tBu)6,Azagly10)-LHRH
• PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHNH2
• (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH
• (D-SER4)-GOSERELIN
• Goserelin EP Impurity L ((D-Leu7)-Goserelin)
• LHRH (1-5)
• H-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2
• Goserelin-d5
• Goserelin EP Impurity G ((D-His2)-Goserelin)
• Goserelin