Basic information Safety Supplier Related

Goserelin EP Impurity G ((D-His2)-Goserelin)

Basic information Safety Supplier Related

Goserelin EP Impurity G ((D-His2)-Goserelin) Basic information

Product Name:
Goserelin EP Impurity G ((D-His2)-Goserelin)
Synonyms:
  • Goserelin EP Impurity G ((D-His2)-Goserelin)
  • Goserelin EP Impurity G
  • Goserelin Impurity 7 (Goserelin EP Impurity G)
  • [2-D-Histidine]goserelin
  • L-Proline, 5-oxo-L-prolyl-D-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-(1,1-dimethylethyl)-L-seryl-L-leucyl-L-arginyl-, 2-(aminocarbonyl)hydrazide
  • (D-His?,D-Ser(tBu)?,Azagly??)-LHRH
  • 800009G
  • Goserelin EP Impurity G TFA Salt
CAS:
1926163-37-2
MF:
C59H84N18O14
MW:
1269.41
Mol File:
1926163-37-2.mol
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Goserelin EP Impurity G ((D-His2)-Goserelin) Chemical Properties

Density 
1.50±0.1 g/cm3(Predicted)
pka
9.82±0.15(Predicted)
Sequence
{Pyr}-{d-His}-Trp-Ser-Tyr-{d-Ser(tBu)}-Leu-Arg-{Pro-Azagly}-NH2
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Goserelin EP Impurity G ((D-His2)-Goserelin) Usage And Synthesis

Uses

(D-His2)-Goserelin is a derivative of Goserelin, a decapeptide analog of gonadotropin-releasing hormone (GnRH/LHRH)[1].

References

[1] Mansi Shah, et al. Capillary electrophoresis methods for impurity profiling of drugs: A review of the past decade. J Pharm Anal. 2022 Feb;12(1):15-28.

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