LHRH (1-5) Chemical Properties

Sequence

{Pyr}-His-Trp-Ser-Tyr

LHRH (1-5) Usage And Synthesis

Uses

LHRH (1-5) (free acid) is a polypeptide generated by the cleavage of LHRH at the Tyr55-Gly66 site. LHRH (1-5) (free acid) is converted into LHRH (1-3) and LHRH (4-5) fragments under the catalysis of Angiotensin-converting enzyme (HY-P2983)[1][2].

References

[1] McDermott JR, et al. Mechanism of degradation of LH-RH and neurotensin by synaptosomal peptidases. Peptides. 1983 Jan-Feb;4(1):25-30. DOI:10.1016/0196-9781(83)90160-2
[2] Yokosawa H, et al. Degradation of luteinizing hormone-releasing hormone by neuroblastoma cells and their membrane: evidence for the involvement of a thiol protease and angiotensin-converting enzyme. J Neurochem. 1987 Jan;48(1):293-8. DOI:10.1111/j.1471-4159.1987.tb13161.x

LHRH (1-5)(52434-75-0)Related Product Information

• Goserelin EP Impurity G ((D-His2)-Goserelin)
• (D-TYR5)-GOSERELIN
• (Ser(tBu)6,Azagly10)-LHRH
• (D-SER6)-GOSERELIN
• (Glu1,D-Ser(tBu)6,Azagly10)-LHRH
• PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHNH2
• (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH
• (D-SER4)-GOSERELIN
• Goserelin EP Impurity L ((D-Leu7)-Goserelin)
• H-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2
• Goserelin-d5
• H-TRP-GLY-GLY-OH
• GLP-HIS-TRP-SER-TYR(ME)-OH
• LHRH (1-5)
• PGLU-HIS-GLY AMIDE
• H-SER-TYR-OH
• SER-PHE
• H-GLY-SER-PHE-OH