Goserelin EP Impurity L ((D-Leu7)-Goserelin) Chemical Properties

Density 

1.50±0.1 g/cm3(Predicted)

pka

9.82±0.15(Predicted)

Sequence

{Pyr}-His-Trp-Ser-Tyr-{d-Ser(tBu)}-{d-Leu}-Arg-Pro-{Azagly}-NH2

Goserelin EP Impurity L ((D-Leu7)-Goserelin) Usage And Synthesis

Uses

(D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].

References

[1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499

Goserelin EP Impurity L ((D-Leu7)-Goserelin)(1926163-38-3)Related Product Information

• Goserelin
• Gonadorelin
• (Ser(tBu)6,Azagly10)-LHRH
• (D-SER6)-GOSERELIN
• (Glu1,D-Ser(tBu)6,Azagly10)-LHRH
• PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHNH2
• (Ser(Ac)4,D-Ser(tBu)6,Azagly10)-LHRH
• (D-SER4)-GOSERELIN
• LHRH (1-5)
• H-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2
• Goserelin-d5
• Goserelin EP Impurity G ((D-His2)-Goserelin)
• (D-TYR5)-GOSERELIN