(D-SER4)-GOSERELIN Chemical Properties

Density 

1.50±0.1 g/cm3(Predicted)

storage temp. 

-15°C

pka

9.82±0.15(Predicted)

Sequence

{Pyr}-His-Trp-{d-Ser}-Tyr-{d-Ser(tBu)}-Leu-Arg-Pro-{Azagly}-NH2

Safety Information

HS Code 

2933790002

(D-SER4)-GOSERELIN Usage And Synthesis

Uses

(D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH)[1].

References

[1] Horvath JE, et al. Effects of long-term treatment with the luteinizing hormone-releasing hormone (LHRH) agonist Decapeptyl and the LHRH antagonist Cetrorelix on the levels of pituitary LHRH receptors and their mRNA expression in rats. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15048-53. DOI:10.1073/pnas.232579499

(D-SER4)-GOSERELIN(1926163-39-4)Related Product Information

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