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2-Acetyl-5-bromothiophene

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2-Acetyl-5-bromothiophene Basic information

Product Name:
2-Acetyl-5-bromothiophene
Synonyms:
  • 5-Bromo 2-acetylthiophene
  • Ethanone, 1-(5-bromo-2-thienyl)-
  • Ethanone,1-(5-bromo-2-thienyl)-
  • Ketone, 5-bromo-2-thienyl methyl
  • 2-Acetyl-5-Bromo Thiophenone
  • 1-(5-Bromothiophene-2-yl)ethanone
  • 2-Bromo-5-acetylthiophene
  • 5-Acetyl-2-bromothiophene
CAS:
5370-25-2
MF:
C6H5BrOS
MW:
205.07
EINECS:
226-363-7
Product Categories:
  • Sulphur Derivatives
  • Thiophenes
  • Thiophene&Benzothiophene
  • Pyridines
  • Building Blocks
  • C4 to C6
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Heterocycle-oher series
Mol File:
5370-25-2.mol
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2-Acetyl-5-bromothiophene Chemical Properties

Melting point:
94-96 °C (lit.)
Boiling point:
103 °C/4 mmHg (lit.)
Density 
1.649 (estimate)
Flash point:
103°C/4mm
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
soluble in Methanol
form 
Crystalline Flakes or Powder
color 
Yellow
Sensitive 
Light Sensitive
BRN 
113949
InChIKey
IGBZCOWXSCWSHO-UHFFFAOYSA-N
CAS DataBase Reference
5370-25-2(CAS DataBase Reference)
NIST Chemistry Reference
2-Acetyl-5-bromothiophene(5370-25-2)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
36/37/39-26-22
RIDADR 
UN2811
WGK Germany 
3
HazardClass 
LIGHT SENSITIVE
HS Code 
29339900

MSDS

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2-Acetyl-5-bromothiophene Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

2-Acetyl-5-bromothiophene was used as a starting reagent in the synthesis of bithiophene bis-imidazo[1,2-a]pyridine derivatives. It was also used in the preparation of phosphorus-containing fused bicyclic 5,6-membered compounds.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 18, p. 1345, 1981 DOI: 10.1002/jhet.5570180714
Synthetic Communications, 11, p. 29, 1981 DOI: 10.1080/00397918108064279

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