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Inabenfide

Basic information Application Safety Supplier Related

Inabenfide Basic information

Product Name:
Inabenfide
Synonyms:
  • SERITARD
  • 4’-chloro-2’-(alpha-hydroxybenzyl)isonicotinanilide
  • cgr-811
  • n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamid
  • n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamide
  • INABENFIDE
  • 4′-Chloro-2′-(α-hydroxybenzyl)isonicotinanilide
  • N-[4-Chloro-2-(hydroxy-phenylmethyl)phenyl]pyridine-4-carboxamide
CAS:
82211-24-3
MF:
C19H15ClN2O2
MW:
338.79
Product Categories:
  • pyridine
Mol File:
82211-24-3.mol
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Inabenfide Chemical Properties

Melting point:
approximate 202℃ (dec.)
Boiling point:
454.6±45.0 °C(Predicted)
Density 
1.2238 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
0-6°C
pka
10.77±0.70(Predicted)
BRN 
7042400
CAS DataBase Reference
82211-24-3(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
29333990
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Inabenfide Usage And Synthesis

Application

Inabenfide (N-[4-chloro-2-(hydroxybenzyl)phenyl]pyridine-4-carboxamide) is a plant growth retardant that inhibits gibberellin synthesis in rice plants, exhibiting strong selective lodging resistance. After application, the number of grains per panicle decreases, but the grain maturity rate increases, leading to an increase in actual yield. Therefore, inabenfide is widely used in rice production.

Definition

ChEBI: Inabenfide is a diarylmethane.

Metabolic pathway

In rats, inabenfide is mainly hydroxylated on the phenyl ring which is not substituted by a chlorine atom through epoxidation. Oxidation of the benzyl alcohol gives benzophenone. The other hydroxylation is the substitution of the chlorine with hydroxyl of the other phenyl ring possessing a chlorine atom. Also, hydrolysis of the amide bond resulting in the corresponding aniline and N-oxidation of the pyridine nitrogen can be observed.

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