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Inabenfide

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Inabenfide Basic information

Product Name:
Inabenfide
Synonyms:
  • SERITARD
  • 4’-chloro-2’-(alpha-hydroxybenzyl)isonicotinanilide
  • cgr-811
  • n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamid
  • n-(4-chloro-2-(hydroxyphenylmethyl)phenyl)-4-pyridinecarboxamide
  • INABENFIDE
  • 4′-Chloro-2′-(α-hydroxybenzyl)isonicotinanilide
  • N-[4-Chloro-2-(hydroxy-phenylmethyl)phenyl]pyridine-4-carboxamide
CAS:
82211-24-3
MF:
C19H15ClN2O2
MW:
338.79
Product Categories:
  • pyridine
Mol File:
82211-24-3.mol
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Inabenfide Chemical Properties

Melting point:
approximate 202℃ (dec.)
Boiling point:
454.6±45.0 °C(Predicted)
Density 
1.2238 (rough estimate)
refractive index 
1.5400 (estimate)
storage temp. 
0-6°C
pka
10.77±0.70(Predicted)
BRN 
7042400
CAS DataBase Reference
82211-24-3(CAS DataBase Reference)
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Safety Information

WGK Germany 
3
HS Code 
29333990
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Inabenfide Usage And Synthesis

Definition

ChEBI: Inabenfide is a diarylmethane.

Metabolic pathway

In rats, inabenfide is mainly hydroxylated on the phenyl ring which is not substituted by a chlorine atom through epoxidation. Oxidation of the benzyl alcohol gives benzophenone. The other hydroxylation is the substitution of the chlorine with hydroxyl of the other phenyl ring possessing a chlorine atom. Also, hydrolysis of the amide bond resulting in the corresponding aniline and N-oxidation of the pyridine nitrogen can be observed.

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