VH 101, phenol
VH 101, phenol Basic information
- Product Name:
- VH 101, phenol
- Synonyms:
-
- E3 ligase Ligand 19
- VH032-cyclopropane-F
- VH 101, phenol
- (2S,4R)-1-((S)-2-(1-fluorocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
- (2S,4R)-1-((S)-2-(1-Fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(2-hydroxy-4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
- Phenolic VH101
- Inhibitor,E3 ligase-recruiting Moiety,inhibit,VHL ligand3,Ligands for E3 Ligase,VH032 cyclopropane F,VH032cyclopropaneF,VHL ligand-3,VH-032-cyclopropane-F
- (2S,4R)-1-[(2S)-2-[(1-fluorocyclopropyl)formamido]-3,3-dimethylbutanoyl]-4-hydroxy-N-{[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CAS:
- 2306193-99-5
- MF:
- C26H33FN4O5S
- MW:
- 532.63
- Mol File:
- 2306193-99-5.mol
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VH 101, phenol Chemical Properties
- Boiling point:
- 841.7±65.0 °C(Predicted)
- Density
- 1.38±0.1 g/cm3(Predicted)
- solubility
- Soluble in DMSO
- pka
- 9.12±0.35(Predicted)
- form
- Solid
- color
- White to yellow
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VH 101, phenol Usage And Synthesis
Uses
VH032-cyclopropane-F (VH 101, phenol) is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal hydroxyl group. Allows rapid conjugation with many linkers containing active leaving groups. A basic building block for development of a protein degrader library.
storage
Store at +4°C
VH 101, phenolSupplier
Jilin Province Woda Biotechnology Co., Ltd. Gold
- Tel
- 13504435624
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Daicel Chiral Technologies (China)CO.,LTD
- Tel
- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
ShangHai Caerulum Pharma Discovery Co., Ltd.
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- 18149758185 18149758185
- sales-cpd@caerulumpharma.com
Shanghai Send Pharmaceutical Technology Co., Ltd.
- Tel
- 021-58088081 Q3252066219
- danping@shsendpharm.com
ShangHai Angti Biotechnology Co., Ltd.
- Tel
- 13764913901
- info@angtibio.com